- Basic information
- CohesinDB ID: CDBP00418569
- Locus: chr21-36722587-36724224
-
Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE116344
-
Cell type: RPE, Fibroblast, RH4, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 57%,
"15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF394, GLIS1, TRP47, POU2F2, SMC1A, FOXA2, ZNF263, MYCN, TOP2A, SS18, ZFX, TEAD4, PAF1, ZNF600, ZBTB48, ZSCAN5A, WT1, FOXA1, TET2, CBX8, SUZ12, ERG3, ERG2, ZNF770, SMARCC1, ZFHX2, YY1, RELA, OGG1, BMI1, ATF3, MYC, SP140, GRHL3, PROX1, PRDM9, SMC3, ZSCAN5D, STAT3, NRIP1, ZNF143, CBX2, CEBPB, CEBPD, ZNF573, SCRT2, SNAI2, NR2F1, EZH2, SMAD5, ESR1, KDM5B, ZNF334, EGR2, CTCF, RXR, EGR1, HSF1, RNF2, SCRT1, JUND, BRD4, MAZ, AATF, ZNF76, STAG1
- Target gene symbol (double-evidenced CRMs): HLCS,CHAF1B,SIM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 32
- Number of somatic mutations (non-coding): 32
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:33025000-33050000~~chr21:36700000-36725000,
chr21:36400000-36425000~~chr21:36700000-36725000,
chr21:36475000-36500000~~chr21:36725000-36750000,
chr21:36500000-36525000~~chr21:36725000-36750000,
chr21:36575000-36600000~~chr21:36725000-36750000,
chr21:36625000-36650000~~chr21:36725000-36750000,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36700000-36725000~~chr21:36900000-36925000,
chr21:36700000-36725000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:36900000-36925000,
chr21:36725000-36750000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:37050000-37075000,
chr21:36727406-36729008~~chr21:36853567-36855599,