- Basic information
- CohesinDB ID: CDBP00418572
- Locus: chr21-36729274-36729976
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 48%,
"13_ReprPC": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, HMG20A, SOX2, XBP1, FOXA1, HLF, SUZ12, RXRB, MLL4, KDM3A, TFAP4, TSC22D4, ATF3, NFIC, THRB, ZFP64, THAP1, MXD4, TP63, ZNF467, KLF5, TEAD1, ELF1, KLF6, KLF10, LMO2, ESR1, OCA2, RCOR2, USF2, CTCF, TCF12, EP300, SOX5, E2F6, DMAP1, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, TFAP2C, MLX, GLIS1, ZSCAN5D, MYCN, HHEX, ZNF263, ZBTB48, ZSCAN5A, STAT1, SRF, GATAD1, DDX5, ZNF485, SAP130, ARID3A, HNF4G, ERG, OGG1, ETS1, EZH1, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, GABPA, APC, XRCC5, ZNF614, STAT3, PRDM14, MIER3, HNRNPH1, NR2F6, NR3C1, CEBPB, CREB1, EZH2, TBL1XR1, BMPR1A, GABPB1, ZHX2, SPI1, HES1, TFE3, MIXL1, ZSCAN2, HDAC2, ZNF644, MXD3, SIX2, FLI1, DRAP1, ZGPAT, HCFC1, HCFC1R1, NFIL3, PTBP1, ETV5, RUNX1, THAP11, MAFG, SMC1A, BCL6, CEBPA, FIP1L1, ZFX, SOX13, SMAD3, TET2, CBX8, TBX3, SP5, ERG3, SMARCC1, RARA, NFYC, RUNX2, GATA4, OSR2, SOX11, ATF2, ZNF48, SMAD4, SMARCB1, CDK8, HMGXB4, MED1, TEAD3, CEBPD, SMAD1, C11orf30, L3MBTL2, MAFK, SP1, NIPBL, USF1, HNF4A, ARID2, REST, ZBTB7A, IKZF5, ATF7, ASH2L, HNRNPLL, FOXP1, AATF, SMC3, STAG1, ETV4, SKI, ZNF283, TRP47, KLF13, ZNF316, FOXA2, PPARG, CREM, PAF1, SS18, ZNF600, MIER2, MAFF, WT1, TCF7, CDK9, HOXB13, ZNF580, FOXO3, KDM1A, YY1, RELA, SP140, ZFP36, HIF1A, GATA3, MGA, MAX, ZNF143, GATA1, CBX2, PLAG1, CEBPG, GFI1B, NR2F2, NR2F1, TCF7L2, KDM5B, TP53, ZNF334, EGR2, ELF3, PHF5A, KAT8, ARID4B, AR, NFKBIZ, BHLHE40, RXR, EGLN2, HSF1, RNF2, ZBTB26, JUND, BRD4, CUX1, MAZ, SMAD4.1D12, AHR
- Target gene symbol (double-evidenced CRMs): TTC3,HLCS,SIM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159263,
ENSG00000159267,
ENSG00000182670,
- Related loop:
chr21:33025000-33050000~~chr21:36700000-36725000,
chr21:36400000-36425000~~chr21:36700000-36725000,
chr21:36475000-36500000~~chr21:36725000-36750000,
chr21:36500000-36525000~~chr21:36725000-36750000,
chr21:36575000-36600000~~chr21:36725000-36750000,
chr21:36625000-36650000~~chr21:36725000-36750000,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36700000-36725000~~chr21:36900000-36925000,
chr21:36700000-36725000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:36900000-36925000,
chr21:36725000-36750000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:37050000-37075000,
chr21:36727406-36729008~~chr21:36853567-36855599,