Deatailed information for cohesin site CDBP00418573

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  • Basic information
  • CohesinDB ID: CDBP00418573
  • Locus: chr21-36730326-36734196
  • Data sourse: ENCSR000BLD, GSE72082, ENCSR000FAD, ENCSR000BLY, GSE105028, GSE131606, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR338DUC, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR167MTG, GSE111913, ENCSR054FKH, ENCSR153HNT
  • Cell type: RPE, H1-hESC, Fibroblast, HCT-116, Hela-Kyoto, Hep-G2, DKO, RT-112, SK-N-SH, K-562, HSPC, H9-hESC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 6% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.867
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "14_ReprPCWk": 42%, "13_ReprPC": 26%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, HMG20A, SOX2, XBP1, FOXA1, HLF, SUZ12, RXRB, MLL4, KDM3A, TFAP4, TSC22D4, ATF3, NFIC, THRB, ZFP64, THAP1, MXD4, TP63, ZNF467, KLF5, TEAD1, ELF1, KLF6, KLF10, LMO2, ESR1, OCA2, RCOR2, USF2, CTCF, TCF12, EP300, SOX5, E2F6, DMAP1, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, TFAP2C, MLX, GLIS1, ZSCAN5D, MYCN, HHEX, ZNF263, ZBTB48, ZSCAN5A, STAT1, SRF, GATAD1, DDX5, ZNF485, SAP130, ARID3A, HNF4G, ERG, OGG1, ETS1, EZH1, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, GABPA, APC, XRCC5, ZNF614, STAT3, PRDM14, MIER3, HNRNPH1, NR2F6, NR3C1, CEBPB, CREB1, EZH2, TBL1XR1, BMPR1A, GABPB1, ZHX2, SPI1, HES1, TFE3, MIXL1, ZSCAN2, HDAC2, ZNF644, MXD3, SIX2, FLI1, DRAP1, ZGPAT, HCFC1, HCFC1R1, NFIL3, PTBP1, ETV5, RUNX1, THAP11, MAFG, SMC1A, BCL6, CEBPA, FIP1L1, ZFX, SOX13, SMAD3, TET2, CBX8, TBX3, SP5, ERG3, SMARCC1, RARA, NFYC, RUNX2, GATA4, OSR2, SOX11, ATF2, ZNF48, SMAD4, SMARCB1, CDK8, HMGXB4, MED1, TEAD3, CEBPD, SMAD1, C11orf30, L3MBTL2, MAFK, SP1, NIPBL, USF1, HNF4A, ARID2, REST, ZBTB7A, IKZF5, ATF7, ASH2L, HNRNPLL, FOXP1, AATF, SMC3, STAG1, ETV4, SKI, ZNF283, TRP47, KLF13, ZNF316, FOXA2, PPARG, CREM, PAF1, SS18, ZNF600, MIER2, MAFF, WT1, TCF7, CDK9, HOXB13, ZNF580, FOXO3, KDM1A, YY1, RELA, SP140, ZFP36, HIF1A, GATA3, MGA, MAX, ZNF143, GATA1, CBX2, PLAG1, CEBPG, GFI1B, NR2F2, NR2F1, TCF7L2, KDM5B, TP53, ZNF334, EGR2, ELF3, PHF5A, KAT8, ARID4B, AR, NFKBIZ, BHLHE40, RXR, EGLN2, HSF1, RNF2, ZBTB26, JUND, BRD4, CUX1, MAZ, SMAD4.1D12, AHR
  • Target gene symbol (double-evidenced CRMs): TTC3,SIM2,HLCS
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 56
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000159263, ENSG00000159267, ENSG00000182670,
  • Related loop: chr21:36475000-36500000~~chr21:36725000-36750000, chr21:36500000-36525000~~chr21:36725000-36750000, chr21:36575000-36600000~~chr21:36725000-36750000, chr21:36625000-36650000~~chr21:36725000-36750000, chr21:36725000-36750000~~chr21:36900000-36925000, chr21:36725000-36750000~~chr21:36925000-36950000, chr21:36725000-36750000~~chr21:37050000-37075000, chr21:36727406-36729008~~chr21:36853567-36855599,
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