- Basic information
- CohesinDB ID: CDBP00418576
- Locus: chr21-36738247-36739054
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 52%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, GLIS1, RUNX1, SMC1A, CEBPA, MYCN, PAF1, ZFX, ZBTB48, WT1, HLF, ZNF205, ERG3, SUZ12, CBX8, ERG2, ZFHX2, BRG1, CHD7, SP140, ZIC2, PRDM1, ZFP36, ATF4, GRHL3, ZNF48, PAX5, MAX, CBX2, NR3C1, CEBPG, CEBPB, TEAD3, CEBPD, SCRT2, KLF9, EGR2, CTCF, TCF12, AR, ZNF479, ZBTB7A, TRIM24, ZBTB42, ZNF146, ZNF366, RNF2, HNRNPLL, U2AF2, MAZ, NFIL3, AHR
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159263,
ENSG00000159267,
ENSG00000182670,
- Related loop:
chr21:36475000-36500000~~chr21:36725000-36750000,
chr21:36500000-36525000~~chr21:36725000-36750000,
chr21:36575000-36600000~~chr21:36725000-36750000,
chr21:36625000-36650000~~chr21:36725000-36750000,
chr21:36725000-36750000~~chr21:36900000-36925000,
chr21:36725000-36750000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:37050000-37075000,