Deatailed information for cohesin site CDBP00418578

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  • Basic information
  • CohesinDB ID: CDBP00418578
  • Locus: chr21-36740699-36741157
  • Data sourse: GSE206145, GSE67783, GSE86191
  • Cell type: RPE, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "14_ReprPCWk": 54%, "15_Quies": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: MBD3, FOXO1, NFIA, TRIM25, PGR, HMG20A, HMGN3, MEIS2, SOX2, XBP1, FOXA1, SUZ12, RBFOX2, RING1B, UBTF, KDM3A, TFAP4, ZNF90, THRB, ATF3, NFIC, BMI1, THAP1, CTCFL, CHD7, PRDM1, ZFP64, CBFB, MXD4, ZNF189, SMARCE1, PAX5, TP63, ZNF736, ZNF467, TEAD1, TRIM28, ELF1, ETV1, SNAI2, KLF6, RBM39, LMO2, ESR1, OCA2, MLL, PITX3, USF2, CTCF, TCF12, JUN, EP300, GATA6, SOX5, DPF2, RYBP, E2F6, DMAP1, TRIM24, E2F4, E2F1, SMC1, TEAD4, FOXA3, KMT2B, GATAD2A, PDX1, TFAP2C, EED, RBPJ, JARID2, POU2F2, NANOG, BRD1, ZSCAN5D, MYCN, ZNF263, TOP2A, ID3, POU5F1, CTBP1, RUNX1T1, ZBTB17, ZBTB48, ZSCAN5A, ZNF649, STAT1, NONO, ERF, GATAD1, DDX5, SAP130, ERG2, SP4, ARID3A, TBP, ERG, OGG1, ZBTB8A, ZNF341, MYC, SMARCA4, EOMES, KDM4A, RAD21, FOXP2, GRHL3, RFX1, PROX1, NKX2-1, RXRA, GABPA, STAT3, XRCC5, APC, NKX3-1, PRDM14, IKZF1, RCOR1, DNMT3B, NR2F6, ZNF614, VDR, INO80, NR3C1, ESRRA, HNRNPL, CREB1, EZH2, CHD8, GRHL2, ZNF652, EBF3, GABPB1, PHF8, ZHX2, SPI1, HBP1, MIXL1, PCBP1, HDAC2, GATA2, GATAD2B, MXD3, SIX2, HCFC1, MXI1, ZGPAT, SMARCA5, NFIL3, MYF5, ATF1, ETV5, PTBP1, RUNX1, THAP11, BCL6, SMC1A, CBX1, EZH2phosphoT487, CEBPA, SIRT6, SIN3A, ZFX, SOX13, FIP1L1, NKX2-2, SMAD3, TET2, ERG3, CBX8, ZNF770, SMARCC1, RARA, ZNF384, NFYC, CREBBP, ZBTB2, TAF15, RUNX2, SMAD2, PRPF4, GATA4, NRF1, ARNT, BACH1, ZNF48, PRDM9, SMAD4, NFYA, ATF2, PBX3, NCAPH2, NR2C1, SMARCB1, CHD1, SNRNP70, HMGXB4, MAFB, MED1, CDK8, ZEB1, TEAD3, CEBPD, KDM6B, SCRT2, ZMYM3, KLF9, L3MBTL2, GTF3C2, ZNF22, RBM22, MAFK, BCL11A, SP1, TFAP2A, HNF4A, USF1, NIPBL, IKZF5, REST, ARID1A, ZBTB7A, RBM25, CCNT2, ARID2, ZHX1, ASH2L, HNRNPLL, TCF3, BCOR, MBD2, FOXP1, AATF, SMC3, STAG1, HMGB1, STAG2, SKI, TRP47, CBFA2T2, ZNF316, AGO1, FOXA2, RBBP5, CREM, PAF1, SS18, ZNF600, PPARG, CHD2, WT1, ESR2, ZBTB33, MEF2C, HOXB13, ZKSCAN1, ZNF580, KDM1A, YY1, RELA, FOXO3, TARDBP, BCL3, NEUROD1, BRG1, SP140, ZFP36, HIF1A, ZIC2, PCGF1, ZNF519, MAF1, MAX, TAL1, NRIP1, ZNF143, AGO2, CBX2, PLAG1, KLF4, CEBPG, GFI1B, NR2F2, NCOA3, ZNF512, NR2F1, KDM5B, TP53, ZNF334, EGR2, ELF3, BHLHE40, AR, ARID4B, TAF1, NFKBIZ, ZNF445, RXR, ZBTB40, ZNF366, HEXIM1, EGR1, TFIIIC, HSF1, RNF2, ZBTB26, SCRT1, BRD4, RB1, CLOCK, JUND, MAZ, TBX2, AHR
  • Target gene symbol (double-evidenced CRMs): HLCS,SIM2,TTC3
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 4
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000159263, ENSG00000159267, ENSG00000182670,
  • Related loop: chr21:36475000-36500000~~chr21:36725000-36750000, chr21:36500000-36525000~~chr21:36725000-36750000, chr21:36575000-36600000~~chr21:36725000-36750000, chr21:36625000-36650000~~chr21:36725000-36750000, chr21:36725000-36750000~~chr21:36900000-36925000, chr21:36725000-36750000~~chr21:36925000-36950000, chr21:36725000-36750000~~chr21:37050000-37075000,
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