- Basic information
- CohesinDB ID: CDBP00418588
- Locus: chr21-36757280-36757952
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BSB, GSE25021, GSE76893, GSE105028, GSE206145, ENCSR000ECE, GSE68388, GSE131606, GSE97394
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Cell type: MCF-7, H1-hESC, HCT-116, HEK293T, Hep-G2, DKO, HUES64, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, FOXA1, INSM2, ATF3, ZNF362, CHD7, ZNF189, SMARCE1, ZNF629, TEAD1, TRIM28, KLF6, NFE2L2, ZNF217, ESR1, CTCF, TCF12, JUN, EP300, MNT, SOX4, SMC1, TEAD4, ZNF175, NANOG, CHD8, POU5F1, ZNF317, ZBTB17, ZBTB48, ZSCAN21, SRF, DDX5, SAP130, ERG, MYC, SMARCA4, TSHZ1, RAD21, NKX2-1, GABPA, NKX3-1, RCOR1, ZNF639, NR3C1, CEBPB, CREB1, GRHL2, FEZF1, SPI1, EHF, IRF1, GATA2, FLI1, MRTFB, ZNF554, ETV5, ZNF585A, SMC1A, NKX2-2, SIN3A, ZFX, SMAD3, SMARCC1, ZBTB2, CREBBP, GATA4, OSR2, ZNF184, GR, ARNT, DAXX, PBX4, ATF2, ZEB2, FOS, CDK8, TEAD3, SCRT2, PIAS1, SMAD1, SETDB1, ZNF22, BCL11A, SP1, ATF7, PHIP, SMC3, NCOR2, STAG1, ZNF394, FOXA2, SS18, ZNF600, ZNF30, HOXB13, RELA, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, SP7, NR2F2, NEUROG2, ZNF334, ELF3, BRD2, BHLHE40, AR, EGLN2, ZNF366, BRD4, JUND, SCRT1, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops