- Basic information
- CohesinDB ID: CDBP00418591
- Locus: chr21-36761443-36762952
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5C, MEIS2, XBP1, PATZ1, ZNF101, FOXA1, PBX2, ZNF596, ZFHX2, ZFP64, RUNX3, PRDM1, IKZF3, ZBTB44, ZNF429, CBFB, ZNF189, PAX5, ZNF467, ZNF629, KLF5, TRIM28, KLF10, LMO2, ESR1, OCA2, ZNF561, CTCF, TCF12, KLF1, ZNF695, LMO1, E2F6, ZNF808, PDX1, GLIS1, POU2F2, BRD1, ZSCAN5D, MYCN, POU5F1, ZSCAN21, ZBTB17, DUX4, ZNF433, ZBTB48, ZSCAN5A, SP4, ERG, ZBTB21, OGG1, ETS1, MYC, SMARCA4, TSHZ1, RAD21, GRHL3, NKX2-1, GABPA, STAT3, ZNF639, CEBPB, KLF8, FEZF1, ZKSCAN5, ZNF257, ZNF182, SIX2, FLI1, ZNF554, RUNX1, MAFG, SIN3A, ZFX, ZNF534, ZNF770, ERG3, TET2, ZNF18, PRDM10, ZNF549, ZNF35, NOTCH1, TAF15, RUNX2, CDK6, OSR2, ZNF184, TFDP1, ATF2, PRDM9, ZEB2, SMAD4, ZNF10, ZEB1, TERF1, ZXDB, MYB, ZNF558, ZNF264, SCRT2, C11orf30, RBM22, MAFK, BCL11A, GSPT2, REST, ZNF479, PHIP, BCOR, PRDM6, STAG1, ZNF394, ZNF283, TRP47, TBL1X, ZNF600, ZSCAN16, ZNF692, WT1, MAFF, ZNF574, CDK9, HOXB13, YY1, RELA, ZNF441, BRCA1, SP140, GATA3, TAL1, MAX, ZFP69B, BCL11B, SP7, TCF7L2, ZNF213, PKNOX1, MYOD1, BRD2, ZNF843, AR, ZNF324, RBAK, ZNF366, ZBTB26, HSF1, BRD4, SCRT1, MAZ, ZSCAN23, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops