Deatailed information for cohesin site CDBP00418594


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00418594
  • Locus: chr21-36766550-36766875
  • Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, ENCSR153HNT
  • Cell type: RPE, HCT-116, RT-112, K-562, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.944
  • Subunit: SA1,Rad21,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 94% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 46%, "15_Quies": 42%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, CHD8, BRD1, TBL1X, MYCN, SIRT6, ZNF263, POU2F2, ZFX, XBP1, ZBTB48, WT1, SMAD3, FOXA1, TET2, TBP, ERG, YY1, RELA, ZNF384, ATF3, CDK6, RAD21, SP140, ARNT, GRHL3, TAL1, ZNF143, AGO2, SNRNP70, CDK8, KLF4, ESRRA, KLF5, ZNF121, KLF6, NR2F1, KDM5B, EZH2, OCA2, GRHL2, CTCF, ELF3, RBM22, SPI1, HNF4A, IRF1, GATA6, HSF1, BRD4, MAZ, SMC3, GTF2F1, STAG1, TFAP2C
  • Target gene symbol (double-evidenced CRMs): HLCS
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 3
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

eachgene