- Basic information
- CohesinDB ID: CDBP00418595
- Locus: chr21-36767128-36767500
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Data sourse: GSE111913, GSE86191
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Cell type: RT-112, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 51%,
"15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, CHD8, BRD1, TBL1X, MYCN, SIRT6, ZNF263, POU2F2, ZFX, XBP1, ZBTB48, WT1, SMAD3, FOXA1, TET2, TBP, ERG, YY1, RELA, ZNF384, ATF3, CDK6, RAD21, SP140, ARNT, GRHL3, TAL1, ZNF143, AGO2, SNRNP70, CDK8, KLF4, ESRRA, KLF5, ZNF121, KLF6, NR2F1, KDM5B, EZH2, OCA2, GRHL2, CTCF, ELF3, RBM22, SPI1, HNF4A, IRF1, GATA6, HSF1, BRD4, MAZ, SMC3, GTF2F1, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 69
- Number of somatic mutations (non-coding): 0
- Related genes and loops