- Basic information
- CohesinDB ID: CDBP00418617
- Locus: chr21-36823587-36823665
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"5_TxWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PATZ1, FOXA1, LEO1, ZFHX2, ATF3, NFIC, CHD7, CBFB, ZSCAN4, HDAC3, ZNF26, SAP30, ESR1, MLL, TP73, USF2, CTCF, TCF12, EP300, BAF155, ZBTB20, MNT, RYBP, E2F6, ZNF423, ZNF350, TEAD4, PDX1, JARID2, GLIS1, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, POU5F1, TOP2A, ZBTB17, ZBTB48, ZSCAN5A, STAT1, DUX4, ERG2, SP4, ERG, ASCL1, OGG1, ZBTB8A, MYC, ONECUT1, SMARCA4, RAD21, GRHL3, APC, STAT3, NKX3-1, ZNF398, VDR, CEBPB, CREB1, FEZF1, GABPB1, SPI1, HDAC2, GATA2, FLI1, MXI1, MRTFB, ZNF554, RUNX1, SMC1A, NKX2-2, SIN3A, ZFX, TET2, ERG3, PRDM10, RARA, RUNX2, CDK6, GATA4, OSR2, NCAPH2, CDK8, ZXDB, MYB, SCRT2, ZMYM3, PIAS1, KLF9, ZNF41, EVI1, RBM22, SP1, BCL11A, RBM25, PHIP, BCOR, GLIS2, FOXP1, AATF, SMC3, STAG1, TRP47, CBFA2T2, TBL1X, FOXA2, RBBP5, PAF1, ZNF600, ZNF692, WT1, HOXB13, KDM1A, YY1, RELA, SP140, ZFP36, ZIC2, HIF1A, OTX2, ZNF519, TAL1, MAX, ZNF143, AGO2, PLAG1, MYOD1, EGR2, BRD2, AR, RXR, ZBTB42, HEXIM1, ZNF366, TFIIIC, HSF1, NOTCH3, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops