- Basic information
- CohesinDB ID: CDBP00418621
- Locus: chr21-36835469-36835862
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Data sourse: GSE86191, ENCSR000EDE, GSE83726, GSE130135, GSE116344, GSE25021, ENCSR000ECS
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Cell type: MCF-7, RH4, HCT-116, HEK293T, HeLa-S3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, ZNF660, XBP1, PATZ1, FOXA1, MLL4, TFAP4, ZFP64, ZBTB44, IKZF3, ZNF273, ZNF189, ZNF320, ZNF467, CDX2, ZNF629, KLF5, ZNF121, KLF10, ZNF561, CTCF, TCF12, BAF155, KLF1, ZBTB20, E2F1, ZNF528, TFAP2C, GLIS1, NANOG, CHD8, ZNF263, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, ZNF317, SP4, ERG, ZBTB21, ZNF585B, ZBTB8A, ZNF341, MYC, RAD21, GRHL3, GABPA, NKX3-1, ZNF750, ZNF93, CREB1, EZH2, FEZF1, KLF17, GATA2, ZNF582, ZNF554, SIN3A, ZFX, AFF4, PRDM10, CREBBP, ZNF35, NOTCH1, RUNX2, CDK6, OSR2, ZNF184, SP3, PBX4, ARNT, ZEB2, SP2, CDK8, CEBPD, MYB, SCRT2, PIAS1, KLF9, BCL11A, ZNF479, ASH2L, PHIP, PRDM6, SMC3, STAG1, ZNF394, ZNF600, ZSCAN16, ZNF692, WT1, HOXB13, YY1, RELA, SP140, TCF4, ZIC2, HIF1A, GATA3, KLF15, MAX, ZNF143, HAND2, KLF4, SP7, NCOA3, NEUROG2, KDM5B, TP53, PKNOX1, ZBTB6, MYOD1, ZNF843, AR, ZNF324, EGLN2, ZBTB42, ZBTB26, NCOR1, SCRT1, BRD4, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops