- Basic information
- CohesinDB ID: CDBP00418629
- Locus: chr21-36852281-36852846
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Data sourse: GSE86191, GSE206145, ENCSR153HNT, GSE83726, GSE116344
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Cell type: K-562, RH4, HCT-116, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 54%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, ZNF468, POU2F2, CHD8, ZFX, XBP1, WT1, ZBTB48, FOXA1, SMARCC1, TFAP4, RELA, ASCL1, NEUROD1, RUNX2, MYC, RAD21, PRDM1, PBX4, ZIC2, TCF4, OTX2, PRDM9, GABPA, TAL1, SPIB, MED1, MAF, TERF1, MYOD1, SPI1, AR, GATA6, ZBTB26, MAZ, SMC3, EED
- Target gene symbol (double-evidenced CRMs): HLCS,SIM2,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:36400000-36425000~~chr21:36850000-36875000,
chr21:36419354-36421097~~chr21:36853698-36855512,
chr21:36500000-36525000~~chr21:36825000-36850000,
chr21:36503297-36505649~~chr21:36853680-36855572,
chr21:36503500-36505460~~chr21:36853738-36855617,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36600000-36625000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36629999-36631989~~chr21:36853631-36855655,
chr21:36629999-36631990~~chr21:36853672-36855599,
chr21:36630020-36631673~~chr21:36853741-36855359,
chr21:36630022-36631930~~chr21:36853698-36855512,
chr21:36630041-36631980~~chr21:36853648-36855688,
chr21:36630061-36631975~~chr21:36853777-36855522,
chr21:36630079-36631909~~chr21:36853738-36855617,
chr21:36630079-36632006~~chr21:36853685-36855567,
chr21:36630135-36631927~~chr21:36853724-36855502,
chr21:36630184-36631672~~chr21:36853762-36855538,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36727406-36729008~~chr21:36853567-36855599,
chr21:36746609-36749083~~chr21:36853704-36855509,
chr21:36746841-36748820~~chr21:36853768-36855574,
chr21:36746942-36748770~~chr21:36853698-36855512,
chr21:36746964-36748885~~chr21:36853704-36855614,
chr21:36746970-36748653~~chr21:36853694-36855322,
chr21:36750000-36775000~~chr21:36850000-36875000,
chr21:36825000-36850000~~chr21:36925000-36950000,