- Basic information
- CohesinDB ID: CDBP00418631
- Locus: chr21-36853815-36855525
-
Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE139435, GSE93080, GSE86191, GSE101921, ENCSR806UKK, GSE51234, GSE120943, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE115248, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE68388, GSE126990
-
Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, Kelly, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, THP-1, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 70% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.267
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 56%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: AR, FOXA2
- Target gene symbol (double-evidenced CRMs): SIM2,CHAF1B,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 39
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:36400000-36425000~~chr21:36850000-36875000,
chr21:36419354-36421097~~chr21:36853698-36855512,
chr21:36429053-36431122~~chr21:36860258-36861974,
chr21:36500000-36525000~~chr21:36825000-36850000,
chr21:36503297-36505649~~chr21:36853680-36855572,
chr21:36503500-36505460~~chr21:36853738-36855617,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36600000-36625000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36629999-36631989~~chr21:36853631-36855655,
chr21:36629999-36631990~~chr21:36853672-36855599,
chr21:36630020-36631673~~chr21:36853741-36855359,
chr21:36630022-36631930~~chr21:36853698-36855512,
chr21:36630041-36631980~~chr21:36853648-36855688,
chr21:36630061-36631975~~chr21:36853777-36855522,
chr21:36630079-36631909~~chr21:36853738-36855617,
chr21:36630079-36632006~~chr21:36853685-36855567,
chr21:36630135-36631927~~chr21:36853724-36855502,
chr21:36630184-36631672~~chr21:36853762-36855538,
chr21:36661133-36662988~~chr21:36853672-36855599,
chr21:36661203-36662789~~chr21:36853762-36855538,
chr21:36661239-36662859~~chr21:36853733-36855333,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36727406-36729008~~chr21:36853567-36855599,
chr21:36746609-36749083~~chr21:36853704-36855509,
chr21:36746841-36748820~~chr21:36853768-36855574,
chr21:36746942-36748770~~chr21:36853698-36855512,
chr21:36746964-36748885~~chr21:36853704-36855614,
chr21:36746970-36748653~~chr21:36853694-36855322,
chr21:36750000-36775000~~chr21:36850000-36875000,
chr21:36825000-36850000~~chr21:36925000-36950000,