- Basic information
- CohesinDB ID: CDBP00418633
- Locus: chr21-36863188-36863633
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Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE72082, ENCSR054FKH, ENCSR153HNT, ENCSR917QNE
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Cell type: K-562, Liver, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: THAP11, ZNF283, BCL6, CEBPA, POU5F1, SOX13, ZFX, DUX4, ERG3, SAP130, SP5, ERG2, RXRB, ZNF580, GATAD1, KDM1A, YY1, RELA, RARA, RUNX2, HOMEZ, RAD21, PRDM1, GRHL3, HIF1A, ARNT, RXRA, DAXX, NRF1, PRDM9, SMAD4, MXD4, APC, PAX5, XRCC5, ZNF614, GATA1, MIER3, NR2F6, KLF4, TEAD3, ELF1, NR2F2, TEAD1, NCOA3, NR2F1, ZNF652, MYOD1, ELF3, CTCF, KAT8, SP1, EP300, MIXL1, HNF4A, ARID4B, SOX5, JUN, IKZF5, HDAC2, ZNF644, SIX2, FLI1, ASH2L, ZBTB26, ZGPAT, FOXP1, PRDM6, NFIL3, FOXA3, GATAD2A, ETV5, RBPJ
- Target gene symbol (double-evidenced CRMs): CHAF1B,HLCS,SIM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:36400000-36425000~~chr21:36850000-36875000,
chr21:36429053-36431122~~chr21:36860258-36861974,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36600000-36625000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36750000-36775000~~chr21:36850000-36875000,