- Basic information
- CohesinDB ID: CDBP00418634
- Locus: chr21-36868703-36869527
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 77%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, ZNF426, CHD8, PPARG, ZNF697, MYCN, ZSCAN5D, ZFX, POU4F2, XBP1, WT1, ZBTB48, ZBTB33, ZNF300, RUNX2, ZFP64, GRHL3, ZIC2, HIF1A, ZNF781, OTX2, ZNF518A, SP2, ZNF143, IKZF1, MED1, NR2F1, ZNF3, ESR1, ZNF334, CTCF, JUN, AR, MXD3, ZNF623, ZC3H11A, ZNF34, STAG1
- Target gene symbol (double-evidenced CRMs): SIM2,HLCS,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 0
- Related genes and loops