- Basic information
- CohesinDB ID: CDBP00418636
- Locus: chr21-36874166-36876283
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Data sourse: GSE67783, GSE86191, GSE206145, ENCSR153HNT, GSE138105
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Cell type: RPE, HCT-116, SLK, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CEBPB, NR2F2, ZFX, PBX4, TP53, SMAD3, BRD4, ESR2, E2F1, STAT3, JUN
- Target gene symbol (double-evidenced CRMs): HLCS,SIM2,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 48
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:36400000-36425000~~chr21:36850000-36875000,
chr21:36575000-36600000~~chr21:36850000-36875000,
chr21:36600000-36625000~~chr21:36850000-36875000,
chr21:36625000-36650000~~chr21:36850000-36875000,
chr21:36650000-36675000~~chr21:36875000-36900000,
chr21:36700000-36725000~~chr21:36850000-36875000,
chr21:36750000-36775000~~chr21:36850000-36875000,