- Basic information
- CohesinDB ID: CDBP00418638
- Locus: chr21-36880756-36882507
-
Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE83726, GSE116344
-
Cell type: RPE, Fibroblast, RH4, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 56%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFATC3, CBFA2T2, CHD8, POU2F2, TOP2A, KDM4C, ZFX, XBP1, WT1, SMAD3, ZBTB48, FOXA1, ZNF770, ERG3, ERG2, CDK9, ZFHX2, RELA, RUNX2, CDK6, MYC, CTCFL, CHD7, RAD21, GRHL3, HIF1A, FOXP2, SP140, MAX, RCOR1, MED1, NR3C1, CEBPB, TRIM28, KDM5B, ESR1, OCA2, NCOA1, HIF2A, EGR2, MYOD1, CTCF, RBM22, PAX3-FOXO1, BRD4, CLOCK, MAZ, SMC3, MYF5, STAG1
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops