- Basic information
- CohesinDB ID: CDBP00418642
- Locus: chr21-36891744-36892476
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE73207
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Cell type: RPE, TF-1, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SMC3,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBFA2T2, ZNF554, CHD8, FOXA2, MYCN, LDB1, MEIS1, POU5F1, ZFX, ZNF600, XBP1, DUX4, WT1, STAT1, ZBTB48, ZSCAN5A, SRF, SMC1A, PBX2, TWIST1, ZNF549, ERG, YY1, RELA, ZBTB8A, NEUROD1, RUNX2, GATA4, OSR2, ISL1, SP140, ARNT, ZIC2, ZNF189, GRHL3, OTX2, GATA3, SMC3, HMBOX1, ZEB2, APC, CBFA2T3, MAX, TAL1, GATA1, STAT3, MITF, RCOR1, HAND2, NFE2, ZNF736, ZFP69B, SP7, GFI1B, TRIM28, SCRT2, ESR1, EBF3, PHOX2B, CTCF, RBM22, USF1, TCF12, BCL11A, AR, HDAC2, GATA2, ZBTB7A, ZBTB42, FLI1, RAD51, GABPA, BRD4, SCRT1, ZNF350, MRTFB, TEAD4, TBX2, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 2
- Related genes and loops