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Basic information

CohesinDB ID: CDBP00418648

Locus: chr21-36912728-36913168

Data sourse: GSE206145, ENCSR153HNT

Cell type: K-562, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 45%, "15_Quies": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, ZSCAN5C, SOX2, XBP1, PATZ1, KDM4B, ZFHX2, HNRNPK, ATF3, THAP1, CHD7, PRDM1, IKZF3, MZF1, TP63, ZNF629, JMJD1C, ZNF121, ESR1, USF2, ZNF561, CTCF, KLF1, ZBTB20, ZNF674, ZNF423, ZNF528, TFAP2C, POU2F2, NANOG, BRD1, POU5F1, MYCN, TOP2A, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, ERG2, SP4, ZNF300, ERG, ZBTB8A, ETS1, MYC, NKX2-1, ZNF398, PRDM14, ZNF639, CEBPB, FEZF1, GRHL2, SPI1, ZNF664, SIX2, RUNX1, EZH2phosphoT487, ZFX, NFKBIA, ZBTB12, TET2, ERG3, ZNF18, PRDM10, SMARCC1, CDK6, OSR2, ZNF184, PBX4, DAXX, ATF2, PRDM9, ZEB2, CBFA2T3, CDK8, ZXDB, MYB, SCRT2, ZNF3, KLF16, ZNF22, RBM22, BCL11A, PHIP, PRDM6, AATF, SMC3, STAG1, ZNF394, TRP47, SS18, ZNF600, ZNF692, WT1, MAFF, MEF2C, HOXB13, YY1, RELA, SP140, ZNF449, GATA1, AGO2, PLAG1, KLF4, ZFP69B, NR2F1, NEUROG2, ZBTB6, ZNF334, EGR2, ZNF140, BRD2, ELF3, AR, ZNF324, ZNF366, ZBTB42, HEXIM1, ZBTB26, NCOR1, HSF1, BRD4, JUND, MAZ, ZNF440, ZSCAN23, ZNF24

Target gene symbol (double-evidenced CRMs): CBR3,HLCS,CHAF1B,SIM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267,

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Deatailed information for cohesin site CDBP00418648