- Basic information
- CohesinDB ID: CDBP00418656
- Locus: chr21-36932869-36933269
-
Data sourse: ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 82%,
"15_Quies": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, FOXA2, ZFX, FOXA1, ERG3, DDX5, ERG2, ZFHX2, YY1, RELA, GRHL3, NKX2-1, MAX, ZFP69B, ZNF334, SETDB1, CTCF, RBM22, PAX8, ZBTB26, BRD4, MAZ, NCOA2, ZNF175, AHR
- Target gene symbol (double-evidenced CRMs): CHAF1B,SIM2,HLCS,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159231,
ENSG00000159259,
ENSG00000159263,
ENSG00000159267,
- Related loop:
chr21:36125000-36150000~~chr21:36925000-36950000,
chr21:36400000-36425000~~chr21:36925000-36950000,
chr21:36418841-36421262~~chr21:36926465-36928856,
chr21:36419097-36421364~~chr21:36926664-36928827,
chr21:36419122-36421037~~chr21:36926683-36929117,
chr21:36419182-36421107~~chr21:36926687-36928814,
chr21:36419184-36421121~~chr21:36926717-36929094,
chr21:36419201-36421142~~chr21:36926513-36928814,
chr21:36419216-36421134~~chr21:36926710-36929115,
chr21:36419217-36421314~~chr21:36926678-36929090,
chr21:36419274-36420828~~chr21:36926717-36928685,
chr21:36419280-36421083~~chr21:36926505-36928808,
chr21:36419354-36421097~~chr21:36926649-36929131,
chr21:36419354-36421097~~chr21:36929169-36930348,
chr21:36419396-36420907~~chr21:36927027-36928493,
chr21:36419406-36420906~~chr21:36927009-36928504,
chr21:36419507-36420817~~chr21:36927023-36928663,
chr21:36421415-36423297~~chr21:36926465-36928856,
chr21:36421419-36423290~~chr21:36926513-36928814,
chr21:36421690-36423243~~chr21:36926866-36928715,
chr21:36421736-36423241~~chr21:36926885-36928641,
chr21:36475000-36500000~~chr21:36925000-36950000,
chr21:36500000-36525000~~chr21:36925000-36950000,
chr21:36503141-36505653~~chr21:36926664-36928827,
chr21:36503201-36505454~~chr21:36926683-36929117,
chr21:36503227-36505444~~chr21:36926436-36929179,
chr21:36503239-36505647~~chr21:36926716-36929066,
chr21:36503245-36505660~~chr21:36926711-36929324,
chr21:36503270-36505647~~chr21:36926678-36929090,
chr21:36503272-36505466~~chr21:36926649-36929131,
chr21:36503276-36505640~~chr21:36926695-36929067,
chr21:36503297-36505454~~chr21:36926751-36928873,
chr21:36503297-36505649~~chr21:36926717-36929094,
chr21:36503300-36505643~~chr21:36926687-36928814,
chr21:36503304-36505537~~chr21:36926465-36928856,
chr21:36503313-36505627~~chr21:36926505-36928808,
chr21:36503329-36505471~~chr21:36926683-36929090,
chr21:36503476-36505662~~chr21:36926726-36928770,
chr21:36503483-36505671~~chr21:36926706-36929092,
chr21:36503492-36505441~~chr21:36926698-36929094,
chr21:36503512-36505449~~chr21:36926642-36928684,
chr21:36503513-36505278~~chr21:36926493-36928737,
chr21:36503555-36505459~~chr21:36926705-36929148,
chr21:36503560-36505442~~chr21:36926670-36928671,
chr21:36503645-36505444~~chr21:36926732-36929011,
chr21:36503774-36505468~~chr21:36926932-36928694,
chr21:36584492-36585859~~chr21:36926709-36929084,
chr21:36625000-36650000~~chr21:36925000-36950000,
chr21:36629965-36632036~~chr21:36926513-36928814,
chr21:36629967-36632038~~chr21:36926717-36929094,
chr21:36629983-36632073~~chr21:36926687-36928814,
chr21:36629992-36632063~~chr21:36926698-36929094,
chr21:36629993-36632017~~chr21:36926436-36929179,
chr21:36629999-36631989~~chr21:36926695-36929067,
chr21:36630009-36632057~~chr21:36926465-36928856,
chr21:36630020-36631673~~chr21:36926943-36928561,
chr21:36630020-36631856~~chr21:36926866-36928715,
chr21:36630022-36631930~~chr21:36926649-36929131,
chr21:36630025-36631987~~chr21:36926664-36928827,
chr21:36630041-36631980~~chr21:36926706-36929092,
chr21:36630043-36632051~~chr21:36926683-36929117,
chr21:36630047-36631984~~chr21:36926713-36929121,
chr21:36630061-36631975~~chr21:36926705-36929148,
chr21:36630069-36631999~~chr21:36926719-36928757,
chr21:36630069-36632004~~chr21:36926505-36928808,
chr21:36630071-36632034~~chr21:36926986-36928735,
chr21:36630079-36631909~~chr21:36926924-36928703,
chr21:36630079-36631971~~chr21:36926751-36928873,
chr21:36630095-36631910~~chr21:36926753-36928677,
chr21:36630100-36631985~~chr21:36926700-36928696,
chr21:36630118-36632028~~chr21:36926726-36928770,
chr21:36630131-36631967~~chr21:36926642-36928684,
chr21:36630135-36631927~~chr21:36926709-36929084,
chr21:36630140-36632034~~chr21:36926410-36929350,
chr21:36630148-36631615~~chr21:36926948-36928575,
chr21:36630184-36631672~~chr21:36926932-36928694,
chr21:36630205-36631735~~chr21:36926885-36928641,
chr21:36630208-36631705~~chr21:36926942-36928578,
chr21:36630216-36631633~~chr21:36927027-36928493,
chr21:36630241-36631581~~chr21:36927031-36928663,
chr21:36639891-36641654~~chr21:36926687-36928814,
chr21:36650000-36675000~~chr21:36925000-36950000,
chr21:36661089-36662805~~chr21:36926942-36928692,
chr21:36661117-36662769~~chr21:36927009-36928504,
chr21:36661144-36662963~~chr21:36926710-36929115,
chr21:36661151-36662948~~chr21:36926649-36929131,
chr21:36661153-36662982~~chr21:36926713-36929121,
chr21:36661155-36662934~~chr21:36926465-36928856,
chr21:36661160-36663028~~chr21:36926687-36928814,
chr21:36661164-36662953~~chr21:36926726-36928770,
chr21:36661178-36662981~~chr21:36926664-36928827,
chr21:36661187-36662898~~chr21:36926505-36928808,
chr21:36661192-36662935~~chr21:36926698-36929094,
chr21:36661198-36662971~~chr21:36926727-36928820,
chr21:36675000-36700000~~chr21:36925000-36950000,
chr21:36700000-36725000~~chr21:36925000-36950000,
chr21:36725000-36750000~~chr21:36925000-36950000,
chr21:36746594-36748679~~chr21:36926513-36928814,
chr21:36746609-36749083~~chr21:36926698-36929094,
chr21:36746645-36749017~~chr21:36926642-36928684,
chr21:36746841-36748820~~chr21:36926678-36929090,
chr21:36746944-36749154~~chr21:36926687-36928814,
chr21:36747017-36748924~~chr21:36926717-36928685,
chr21:36747198-36748728~~chr21:36926753-36928677,
chr21:36747249-36749170~~chr21:36926465-36928856,
chr21:36747295-36748582~~chr21:36926942-36928578,
chr21:36825000-36850000~~chr21:36925000-36950000,
chr21:36925000-36950000~~chr21:38350000-38375000,