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Basic information

CohesinDB ID: CDBP00418658

Locus: chr21-36936430-36937373

Data sourse: GSE67783, GSE120943, ENCSR153HNT, GSE86191

Cell type: K-562, Monocytes, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 54%, "5_TxWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, MYCN, RUNX1T1, TOP2A, ZFX, ZNF600, XBP1, WT1, ZBTB48, ZSCAN5A, TET2, LEO1, YY1, RELA, SP140, ZNF143, ZNF467, KDM5B, ZBTB6, ZNF334, CTCF, RBM22, AR, FLI1, ZBTB26, NOTCH3, BRD4, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): CHAF1B,SIM2,CBR3,HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 411

Number of somatic mutations (non-coding): 122

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267,

eachgene

Deatailed information for cohesin site CDBP00418658