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Basic information

CohesinDB ID: CDBP00418662

Locus: chr21-36941642-36942402

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT

Cell type: K-562, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 85%, "15_Quies": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SKI, ZNF384, CEBPB, CEBPA, TRIM28, ZNF362, ZFX, WT1, BRD4, PAX5, KMT2B, SPI1

Target gene symbol (double-evidenced CRMs): HLCS,CBR3,CHAF1B,SIM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 21

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267,

eachgene

Deatailed information for cohesin site CDBP00418662