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Basic information

CohesinDB ID: CDBP00418663

Locus: chr21-36945889-36946126

Data sourse: GSE143937, ENCSR153HNT

Cell type: K-562

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 75%, "15_Quies": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NCOA2, CBFA2T2, CEBPA, LDB1, HDAC1, POU5F1, ZNF263, MEIS2, CTBP1, MTA2, MTA3, ZBTB48, FOXA1, ZNF770, NBN, PBX2, CDK9, ERG, YY1, ZNF384, TARDBP, NEUROD1, ATF3, RUNX2, JUNB, SMARCA4, RFX1, ARID1B, MYC, PRDM1, ARNT, GRHL3, TFDP1, HMBOX1, ZEB2, TAL1, CBFA2T3, SMARCE1, MAX, GATA1, IKZF1, MITF, RCOR1, NR2F6, MED1, CEBPG, CEBPB, NR3C1, ESRRA, NR2F2, CEBPD, MYB, ELF1, NR2F1, EZH2, PKNOX1, L3MBTL2, CTCF, TCF12, RBM22, BCL11A, E4F1, EP300, HES1, DPF2, HDAC2, REST, GATA2, IRF4, ZNF146, SOX6, ATF7, ASH2L, NCOR1, RNF2, BRD4, ILF3, HNRNPLL, MYNN, TEAD4, ZNF24, MLLT1

Target gene symbol (double-evidenced CRMs): CBR3,CHAF1B,HLCS,SIM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 21

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000159231, ENSG00000159259, ENSG00000159263, ENSG00000159267,

eachgene

Deatailed information for cohesin site CDBP00418663