- Basic information
- CohesinDB ID: CDBP00418669
- Locus: chr21-36957810-36958241
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 82%,
"15_Quies": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, PGR, SMC1A, TBL1X, LDB1, ZNF263, AGO1, MYCN, ZFX, FOXA2, XBP1, SIRT6, ZBTB48, WT1, ZNF600, FOXA1, CTBP1, ZNF662, ZBTB33, ERG3, RBFOX2, ERG2, HLF, TBP, ZFHX2, ERG, YY1, RELA, OGG1, ATF3, RUNX2, GATA4, SP140, GRHL3, PRDM1, SOX11, ATF4, CBFB, HMBOX1, ZNF189, MECOM, CBFA2T3, STAT3, TP63, GATA1, AGO2, IKZF1, ZNF143, ZNF467, KLF4, CEBPB, NR3C1, NCOA3, KDM6B, TRIM28, ZNF680, EZH2, ESR1, PKNOX1, GRHL2, ZNF334, EGR2, CTCF, RBM22, BCL11A, SPI1, AR, GATA6, MXD3, HEXIM1, FLI1, HSF1, NOTCH3, MAZ, AATF, HCFC1R1, SMC3, GTF2F1, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): DYRK1A,HLCS,TTC3,VPS26C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops