- Basic information
- CohesinDB ID: CDBP00418674
- Locus: chr21-36973649-36974411
-
Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, ENCSR000ECS
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Cell type: RPE, Fibroblast, HCT-116, HeLa-S3, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SMC3,Rad21,SA1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 54%,
"5_TxWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF257, SP7, TEAD1, ZNF317, ZBTB17, GRHL3, RBM22
- Target gene symbol (double-evidenced CRMs): VPS26C,DYRK1A,TTC3,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
- Related loop:
chr21:31725000-31750000~~chr21:36975000-37000000,
chr21:36950000-36975000~~chr21:37050000-37075000,
chr21:36950000-36975000~~chr21:37075000-37100000,
chr21:36950000-36975000~~chr21:37250000-37275000,
chr21:36950000-36975000~~chr21:37350000-37375000,
chr21:36950000-36975000~~chr21:37550000-37575000,
chr21:36975000-37000000~~chr21:37075000-37100000,
chr21:36975000-37000000~~chr21:37200000-37225000,
chr21:36975000-37000000~~chr21:37225000-37250000,
chr21:36975000-37000000~~chr21:37250000-37275000,
chr21:36975000-37000000~~chr21:37350000-37375000,
chr21:36975000-37000000~~chr21:37475000-37500000,
chr21:36975000-37000000~~chr21:37550000-37575000,
chr21:36975000-37000000~~chr21:37625000-37650000,
chr21:36975000-37000000~~chr21:37650000-37675000,
chr21:36975000-37000000~~chr21:37850000-37875000,
chr21:36975000-37000000~~chr21:37900000-37925000,
chr21:36975000-37000000~~chr21:38125000-38150000,
chr21:36976114-36978430~~chr21:37009040-37011094,
chr21:36976114-36978430~~chr21:37086465-37088179,
chr21:36976280-36978448~~chr21:36989013-36991518,
chr21:36976280-36978448~~chr21:37009094-37011139,
chr21:36976280-36978448~~chr21:37078697-37080394,
chr21:36976280-36978448~~chr21:37086131-37087976,
chr21:36976388-36978333~~chr21:37009080-37011137,
chr21:36976391-36978395~~chr21:36988956-36991174,
chr21:36976392-36978397~~chr21:37009089-37011147,
chr21:36976394-36978416~~chr21:37009250-37011101,
chr21:36976394-36978416~~chr21:37086094-37088173,
chr21:36976402-36978434~~chr21:37086106-37088263,
chr21:36976404-36978374~~chr21:37086393-37088124,
chr21:36976407-36978411~~chr21:37009056-37011247,
chr21:36976407-36978411~~chr21:37086055-37088195,
chr21:36976409-36978425~~chr21:37009116-37011027,
chr21:36976410-36978425~~chr21:37009307-37011128,
chr21:36976410-36978425~~chr21:37581857-37583566,
chr21:36976414-36978410~~chr21:37581771-37583697,
chr21:36976414-36978490~~chr21:37009170-37010886,
chr21:36976414-36978490~~chr21:37118786-37120541,
chr21:36976414-36978490~~chr21:37581977-37583577,
chr21:36976416-36978177~~chr21:37079107-37080371,
chr21:36976420-36977983~~chr21:37009274-37010871,
chr21:36976420-36978300~~chr21:37009165-37010905,
chr21:36976420-36978406~~chr21:36989198-36991097,
chr21:36976420-36978406~~chr21:37009183-37010907,
chr21:36976420-36978417~~chr21:37086403-37088182,
chr21:36976425-36978091~~chr21:37009147-37011170,
chr21:36976426-36978435~~chr21:37086473-37087963,
chr21:36976427-36978248~~chr21:37086150-37088199,
chr21:36976430-36978401~~chr21:37086077-37088227,
chr21:36976435-36978463~~chr21:37009096-37011260,
chr21:36976435-36978463~~chr21:37086055-37088213,
chr21:36976439-36978624~~chr21:36989354-36991335,
chr21:36976458-36978476~~chr21:36989166-36991059,
chr21:36976463-36978161~~chr21:37009171-37010708,
chr21:36976463-36978487~~chr21:37009057-37010910,