- Basic information
- CohesinDB ID: CDBP00418691
- Locus: chr21-36999928-37001231
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE121355, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE25021, GSE93080, GSE143937, GSE67783, ENCSR000BKV, GSE138405, GSE76893, GSE152721, GSE206145-NatGen2015, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE145327, ENCSR000EEG, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR956LGB, GSE110061, GSE129526, GSE111913, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS
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Cell type: RH4, GM19240, HSPC, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HeLa-S3, GM2255, IMR-90, K-562, DKO, GM18526, H1-hESC, GM12878, GM12891, GM2588, SK-N-SH, RT-112, GM19099, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, A-549, GM19238, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 20% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.667
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 56%,
"15_Quies": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: JARID2, CHD8, MYCN, ZFX, ZNF317, ZBTB48, ZNF770, RELA, MCM3, SP140, XRCC5, MAX, HNRNPH1, NR3C1, EZH2, OCA2, BCL11A, SCRT1, BRD4, BCOR, MAZ, SMC3, AHR
- Target gene symbol (double-evidenced CRMs): KCNJ6,VPS26C,TTC3,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:31725000-31750000~~chr21:36975000-37000000,
chr21:36975000-37000000~~chr21:37075000-37100000,
chr21:36975000-37000000~~chr21:37200000-37225000,
chr21:36975000-37000000~~chr21:37225000-37250000,
chr21:36975000-37000000~~chr21:37250000-37275000,
chr21:36975000-37000000~~chr21:37350000-37375000,
chr21:36975000-37000000~~chr21:37475000-37500000,
chr21:36975000-37000000~~chr21:37550000-37575000,
chr21:36975000-37000000~~chr21:37625000-37650000,
chr21:36975000-37000000~~chr21:37650000-37675000,
chr21:36975000-37000000~~chr21:37850000-37875000,
chr21:36975000-37000000~~chr21:37900000-37925000,
chr21:36975000-37000000~~chr21:38125000-38150000,
chr21:36999877-37001750~~chr21:37078770-37080416,
chr21:36999885-37001435~~chr21:37078647-37080436,
chr21:36999930-37001432~~chr21:37078697-37080394,
chr21:36999934-37001381~~chr21:37086150-37088199,