Deatailed information for cohesin site CDBP00418695

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  • Basic information
  • CohesinDB ID: CDBP00418695
  • Locus: chr21-37009443-37011358
  • Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE36578, GSE101921, ENCSR806UKK, GSE51234, GSE120943, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE115248, GSE168045, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, ENCSR193NSH, ShirahigeLab, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, ShirahigeLab-GSE177045, GSE72082, ENCSR501LQA, GSE116868, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, ShirahigeLab-NatGen2015, GSE138105, ENCSR703TNG, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
  • Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, THP-1, Ishikawa, Kelly, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, HUES9, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, SC, A-549, HUVEC, HCAEC, GM19238, HeLa, BGO3, TC-71, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 74% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.200
  • Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 90% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "14_ReprPCWk": 24%, "13_ReprPC": 18%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, ZNF616, FOXA1, RXRB, MLL4, KDM3A, HDGF, MEN1, ZBTB44, ZNF322, MORC2, PAX5, ZNF320, TEAD1, ZNF121, LMO2, OCA2, PITX3, ZNF561, SOX5, DEK, E2F4, ZNF528, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, BRD3, CTBP1, ERF, DUX4, STAT1, ZNF563, SAP130, ERG, ZBTB8A, EZH1, SMARCA4, RFX1, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, HCFC1, MXI1, RELB, RUNX1, CEBPA, NKX2-2, HDAC1, IRF3, REPIN1, ZNF654, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, ZBTB2, TFDP1, ATF2, SMARCB1, ZNF331, PIAS1, SMAD1, C11orf30, MBD1, IKZF5, ARID2, ZSCAN31, ZNF605, MBD2, ELL2, HMGB1, NFATC3, CBFA2T2, MEF2B, CBX3, ZNF207, CREM, CHD2, PAF1, ZSCAN16, WT1, MEF2C, NEUROD1, ZFP36, BATF, MAF1, SPIB, ZNF333, PLAG1, KLF4, BCL11B, ZFP69B, ZBTB6, MED, EGR2, RBM14, ELF3, ARID4B, RXR, EGLN2, HSF1, ZBTB26, SCRT1, ILF3, ZNF316, ZNF660, XBP1, HNF1A, KDM4B, PBX2, HNRNPK, ATF3, THRB, ZFP64, RUNX3, CBFB, TP63, ZSCAN4, JMJD1C, MAF, ELF1, RBM39, SNAI2, JUN, CTCF, TAF3, ZBTB20, LMO1, RYBP, DPF2, IRF4, ZNF423, ZNF280A, PDX1, TFAP2C, RBPJ, MLX, ZNF239, MTA2, ZSCAN21, ZBTB48, ZBTB17, ZNF317, NONO, SRF, DDX5, NBN, ZNF25, ONECUT1, KDM4A, ZNF2, HOMEZ, FOXP2, RXRA, NKX3-1, MIER3, HNRNPH1, TERF2, VDR, NR3C1, KMT2A, ZBTB11, TBL1XR1, KLF8, GRHL2, EBF3, ZBTB14, ZNF146, SMARCA5, NFIL3, THAP11, ZNF585A, EZH2phosphoT487, LDB1, SOX13, AFF4, ZMIZ1, SP3, ARNT, BACH1, ZNF48, ZEB2, NFYA, HMBOX1, PBX3, NCAPH2, MAFB, ZNF10, HMGXB4, TEAD3, ZXDB, ZNF680, KLF9, USF1, BCL11A, SP1, ZNF479, ATF7, ASH2L, PCGF2, CTBP2, GLIS2, PRDM6, ZNF623, SMC3, STAG1, MLLT1, STAG2, ZNF394, TRP47, AGO1, MTA3, EBF1, MAFF, ZNF580, ZKSCAN1, KDM1A, ZNF502, BRG1, ZIC2, PCGF1, GATA3, KLF15, TAL1, ZNF143, AGO2, MTA1, ZNF768, TP53, ZNF334, ZSCAN22, NFKB1, PHOX2B, BRD2, PHF5A, KAT8, ARRB1, TBX21, RB1, TFIIIC, RNF2, IKZF2, BRD4, JUND, CUX1, ZSCAN23, ZNF468, PGR, SOX2, PATZ1, RING1B, UBTF, TFAP4, SIN3B, SETX, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, SAP30, ESR1, ZNF217, KLF1, ZNF695, SOX9, ZNF260, E2F6, TRIM24, RFX5, PRKDC, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, ERG2, SP4, TBP, HOXC5, OGG1, SMARCC2, ETS1, MYC, ARID1B, ZNF24, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, DNMT3B, EZH2, ZNF652, PHF8, SPI1, ZNF786, ZNF202, PCBP1, HDAC2, GATAD2B, ZNF76, ZNF554, NFYB, ETV5, BCL6, SIN3A, ZBTB12, ERG3, RARA, ZNF384, CREBBP, ZNF35, TAF15, NFYC, SMAD4, ZNF518A, CDK8, ZEB1, ZNF264, ZNF22, MAFK, HNF4A, REST, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF30, ZNF574, TCF7, RELA, TARDBP, SKIL, MAX, GFI1B, NR2F1, NEUROG2, KDM5B, TCF7L2, PKNOX1, MYOD1, AR, ZNF445, YAP1, ZNF324, HEXIM1, DMAP1, AHR, MBD3, FOSL2, ZNF391, HMG20A, SUZ12, RBFOX2, ZNF28, ZFHX2, CTCFL, PRDM1, KLF14, ZNF736, ZNF629, ZNF506, KLF5, TRIM28, BCLAF1, RCOR2, HNF1B, USF2, TCF12, EP300, BAF155, GATA6, SOX6, ZNF512B, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, RUNX1T1, ID3, CDK7, ZNF649, GATAD1, ARID3A, ZNF300, ASCL1, ZNF341, RAD21, GRHL3, XRCC5, ZNF614, NFE2, ZNF667, ZNF639, JMJD6, HBP1, TFE3, IRF1, ZGPAT, ZNF418, ZNF766, MRTFB, ATF1, PTBP1, SMC1A, CBX1, SIRT6, ZNF335, ZFX, ZNF534, FIP1L1, SMAD3, TWIST1, IRF2, PRPF4, NOTCH1, RUNX2, ZSCAN30, GATA4, OSR2, ZNF184, CDK6, NRF1, PBX4, CHD1, FOS, MED1, KDM6B, CEBPD, SCRT2, MYB, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, TAF2, SKI, ZNF283, FOXA2, RBBP5, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, ZNF610, SP140, HIF1A, OTX2, ZNF519, ZNF449, GATA1, HAND2, CEBPG, SP7, NCOA3, ZNF687, ZNF213, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MYNN, MAZ, BRCA1
  • Target gene symbol (double-evidenced CRMs): HLCS
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000159267,
  • Related loop: chr21:36629967-36632038~~chr21:37009098-37011099, chr21:36630079-36631909~~chr21:37009057-37010910, chr21:36938297-36940389~~chr21:37009089-37011147, chr21:36938603-36940392~~chr21:37009094-37011139, chr21:36938709-36940332~~chr21:37009131-37010729, chr21:36938795-36940479~~chr21:37009057-37010910, chr21:36938878-36940353~~chr21:37009171-37010708, chr21:36976114-36978430~~chr21:37009040-37011094, chr21:36976280-36978448~~chr21:37009094-37011139, chr21:36976388-36978333~~chr21:37009080-37011137, chr21:36976392-36978397~~chr21:37009089-37011147, chr21:36976394-36978416~~chr21:37009250-37011101, chr21:36976407-36978411~~chr21:37009056-37011247, chr21:36976409-36978425~~chr21:37009116-37011027, chr21:36976410-36978425~~chr21:37009307-37011128, chr21:36976414-36978490~~chr21:37009170-37010886, chr21:36976420-36977983~~chr21:37009274-37010871, chr21:36976420-36978300~~chr21:37009165-37010905, chr21:36976420-36978406~~chr21:37009183-37010907, chr21:36976425-36978091~~chr21:37009147-37011170, chr21:36976435-36978463~~chr21:37009096-37011260, chr21:36976463-36978161~~chr21:37009171-37010708, chr21:36976463-36978487~~chr21:37009057-37010910,
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