- Basic information
- CohesinDB ID: CDBP00418713
- Locus: chr21-37045062-37045669
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Data sourse: GSE98367, GSE50893, ENCSR153HNT, GSE73207
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Cell type: K-562, TF-1, SNYDER, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC1,SA1,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, XBP1, TFAP4, LYL1, ATF3, THAP1, CBFB, MECOM, MITF, ZNF736, JMJD1C, TEAD1, TRIM28, LMO2, ESR1, OCA2, CTCF, TCF12, LMO1, GATA6, TFAP2C, EED, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, RUNX1T1, CDK7, ZBTB48, ZSCAN5A, STAT1, MLLT3, DDX5, ERG, PBX1, ETS1, MYC, FOXP2, GRHL3, GABPA, PRDM14, ZNF285, NR3C1, CEBPB, KMT2A, EZH2, GABPB1, SPI1, MIXL1, GATA2, INTS13, MXD3, FLI1, ZGPAT, ETV5, RUNX1, SMC1A, CEBPA, ZFX, RARA, ZNF384, TAF15, ARNT, ZNF48, ETV6, CDK8, TEAD3, TERF1, CEBPD, MYB, EVI1, STAT5A, SP1, BCL11A, NR4A1, TCF3, SMC3, STAG1, NFATC3, SKI, ZNF816, TRP47, EBF1, MEIS1, GTF2B, WT1, CDK9, HOXB13, ZKSCAN1, KDM1A, RELA, SP140, ZIC2, TCF4, GATA3, TAL1, MAX, ZNF143, GATA1, PLAG1, BCL11B, NCOA3, NR2F2, NR2F1, MED, ZNF334, AR, ZBTB16, RXR, HEXIM1, HSF1, ZBTB26, BRD4, MAZ, ZFP42, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops