- Basic information
- CohesinDB ID: CDBP00418714
- Locus: chr21-37046570-37047834
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Data sourse: GSE67783, GSE72082, GSE86191, GSE116868, GSE111913, GSE105028, ENCSR153HNT, GSE68388
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Cell type: HCT-116, Hep-G2, MB157, RT-112, K-562, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 48%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CTNNB1, POU5F1, ZFX, ZBTB48, WT1, SMAD3, FOXA1, ZBTB33, ERG3, ERG2, ZFHX2, YY1, RELA, CREBBP, RFX1, RAD21, GRHL3, ARNT, DAXX, XRCC5, MAX, ZNF143, FOS, ZNF398, NFE2, MED1, CDX2, CEBPB, KLF5, TEAD3, TFAP2C, NR2F1, KDM5B, TP53, C11orf30, EGR2, GABPB1, T, BRD2, NIPBL, HNF4A, KLF17, NCOR1, BRD4, JUND, TCF3, SMC3, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops