- Basic information
- CohesinDB ID: CDBP00418728
- Locus: chr21-37082890-37083573
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Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE72082, ENCSR000BLS, ENCSR054FKH, GSE73207, ENCSR000EDW, ENCSR917QNE
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Cell type: Liver, TF-1, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 33%,
"7_Enh": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, LCORL, HMGN3, NME2, MEIS2, XBP1, FOXA1, HLF, RXRB, PBX2, LEO1, KDM3A, TFAP4, HDGF, THRB, NFIC, ATF3, ZFP64, PRDM1, MXD4, SMARCE1, PAX5, TEAD1, TRIM28, ELF1, KLF6, NFE2L2, RCOR2, ESR1, MLL, OCA2, CTCF, TCF12, JUN, EP300, BAF155, L3MBTL4, MNT, E4F1, SOX5, GATA6, DPF2, TRIM24, SOX6, RFX3, TEAD4, FOXA3, ZNF175, GATAD2A, GTF2F1, RBPJ, MLX, EHMT2, CHD8, POU5F1, HHEX, RUNX1T1, CTBP1, MTA2, ZBTB48, STAT1, MLLT3, GATAD1, SAP130, NBN, ARID3A, HNF4G, ERG, ONECUT1, MYC, SMARCA4, RFX1, ARID1B, HOMEZ, RAD21, GRHL3, RXRA, FOXK2, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, MIER3, RCOR1, NR2F6, LEF1, NFE2, NR3C1, CEBPB, CREB1, CCAR2, EZH2, GRHL2, ZNF652, TRPS1, GABPB1, HES1, SPI1, TFE3, MIXL1, HBP1, HDAC2, GATA2, ZNF644, DRAP1, ZGPAT, SMARCA5, NFIL3, ZNF554, ETV5, CC2D1A, RUNX1, THAP11, BCL6, SMC1A, CEBPA, HDAC1, NKX2-2, LDB1, SOX13, SIN3A, ZNF534, TBX3, SP5, SMARCC1, MYBL2, RARA, ZNF384, NFYC, RUNX2, GATA4, NRF1, ARNT, ZNF48, SMAD4, HMBOX1, ZEB2, ETV6, CBFA2T3, FOXM1, SMARCB1, HMGXB4, CHD1, TGIF2, SUPT5H, MED1, TEAD3, ZEB1, CEBPD, PML, PIAS1, ZMYM3, ZNF3, STAT5A, KLF16, RBM22, MAFK, SP1, NIPBL, BCL11A, HNF4A, IKZF5, RBM25, CCNT2, ASH2L, AFF1, BCOR, FOXP1, SMC3, MLLT1, ETV4, SKI, CBFA2T2, PPARG, FOXA2, ZNF316, CREM, MEIS1, CBX3, E2F8, MIER2, ZNF600, GTF2B, ZBTB33, TCF7, MEF2C, CDK9, ZNF580, HOXB13, KDM1A, YY1, RELA, NEUROD1, AHR, ZFP36, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, GATA1, CEBPG, GFI1B, NR2F2, PKNOX1, ELF3, PHF5A, KAT8, ARID4B, AR, NFKBIZ, BHLHE40, ZBTB40, EGLN2, ZBTB26, HSF1, NOTCH3, BRD4, JUND, SCRT1, ILF3, CUX1, NCOR1, RNF2, IRF9, ZNF24, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): TTC3,HLCS,CHAF1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159267,
ENSG00000182670,
- Related loop:
chr21:36400000-36425000~~chr21:37075000-37100000,
chr21:36938850-36940337~~chr21:37086674-37088107,
chr21:36950000-36975000~~chr21:37075000-37100000,
chr21:36975000-37000000~~chr21:37075000-37100000,
chr21:36976114-36978430~~chr21:37086465-37088179,
chr21:36976280-36978448~~chr21:37078697-37080394,
chr21:36976280-36978448~~chr21:37086131-37087976,
chr21:36976394-36978416~~chr21:37086094-37088173,
chr21:36976402-36978434~~chr21:37086106-37088263,
chr21:36976404-36978374~~chr21:37086393-37088124,
chr21:36976407-36978411~~chr21:37086055-37088195,
chr21:36976416-36978177~~chr21:37079107-37080371,
chr21:36976420-36978417~~chr21:37086403-37088182,
chr21:36976426-36978435~~chr21:37086473-37087963,
chr21:36976427-36978248~~chr21:37086150-37088199,
chr21:36976430-36978401~~chr21:37086077-37088227,
chr21:36976435-36978463~~chr21:37086055-37088213,
chr21:36989316-36991217~~chr21:37086306-37088100,
chr21:36999877-37001750~~chr21:37078770-37080416,
chr21:36999885-37001435~~chr21:37078647-37080436,
chr21:36999930-37001432~~chr21:37078697-37080394,
chr21:36999934-37001381~~chr21:37086150-37088199,
chr21:37078878-37080096~~chr21:37582024-37583384,