- Basic information
- CohesinDB ID: CDBP00418732
- Locus: chr21-37089506-37089981
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, ENCSR153HNT
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Cell type: K-562, Fibroblast, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 59%,
"4_Tx": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, MYC, NFIC, ZBTB26, PRDM1, ARNT, ZBTB48, GATAD1, RBM22, SUPT5H
- Target gene symbol (double-evidenced CRMs): CHAF1B,TTC3,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159259,
ENSG00000159267,
ENSG00000182670,
- Related loop:
chr21:36400000-36425000~~chr21:37075000-37100000,
chr21:36938850-36940337~~chr21:37086674-37088107,
chr21:36950000-36975000~~chr21:37075000-37100000,
chr21:36975000-37000000~~chr21:37075000-37100000,
chr21:36976114-36978430~~chr21:37086465-37088179,
chr21:36976280-36978448~~chr21:37086131-37087976,
chr21:36976394-36978416~~chr21:37086094-37088173,
chr21:36976402-36978434~~chr21:37086106-37088263,
chr21:36976404-36978374~~chr21:37086393-37088124,
chr21:36976407-36978411~~chr21:37086055-37088195,
chr21:36976420-36978417~~chr21:37086403-37088182,
chr21:36976426-36978435~~chr21:37086473-37087963,
chr21:36976427-36978248~~chr21:37086150-37088199,
chr21:36976430-36978401~~chr21:37086077-37088227,
chr21:36976435-36978463~~chr21:37086055-37088213,
chr21:36989316-36991217~~chr21:37086306-37088100,
chr21:36999934-37001381~~chr21:37086150-37088199,