- Basic information
- CohesinDB ID: CDBP00418741
- Locus: chr21-37119296-37120160
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE25021, ENCSR000BKV, GSE76893, GSE152721, GSE130135, GSE116344, GSE106870, ENCSR000EEG, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR167MTG, GSE129526, ENCSR054FKH, GSE83726
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Cell type: MCF-7, H1-hESC, HCT-116, RH4, HEK293T, Hep-G2, CVB-hiPSC, HUES64, K-562, SK-N-SH, CVI-hiPSC, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 63%,
"4_Tx": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZNF660, SOX2, XBP1, PATZ1, FOXA1, PBX2, ZFHX2, TFAP4, ATF3, ZBTB44, PRDM1, IKZF3, RUNX3, ZNF273, ZNF189, TP63, ZNF629, ESR1, OCA2, JUN, CTCF, GATA6, IRF4, E2F1, ZNF528, ZNF175, GATAD2A, GLIS1, CHD8, POU5F1, BRD3, ZNF263, ZSCAN21, ZBTB17, ZBTB48, ZNF317, SRF, BAHD1, ERG2, ERG, ZBTB21, ZNF329, ZNF341, MYC, HOMEZ, RAD21, GRHL3, GABPA, ZNF750, NR3C1, CREB1, EZH2, FEZF1, SPI1, ZNF664, GATA2, GATAD2B, RELB, SMC1A, LDB1, ZNF335, SMAD3, ERG3, PRDM10, NSD2, ZBTB2, ZNF35, RUNX2, CDK6, GATA4, OSR2, GR, PBX4, ARNT, ZNF518A, ETV6, FOS, SUPT5H, ZNF680, SCRT2, SMAD1, RBM22, USF1, BCL11A, ASH2L, PHIP, PRDM6, SMC3, STAG1, ZNF394, ZNF283, FOXA2, ZNF600, MIER2, ZNF692, ZSCAN16, ZNF574, CDK9, YY1, RELA, JUNB, ZIC2, HIF1A, OTX2, GATA3, BATF, TAL1, NRIP1, GATA1, ZNF143, SP7, PKNOX1, ZSCAN22, BCL6B, EGR2, NFKB1, ELF3, BRD2, BHLHE40, AR, ZNF324, ZBTB42, ZNF366, MYNN, NOTCH3, JUND, SCRT1, BRD4, ZNF24
- Target gene symbol (double-evidenced CRMs): HLCS,TTC3,KCNJ6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 0
- Related genes and loops