- Basic information
- CohesinDB ID: CDBP00418745
- Locus: chr21-37139577-37140371
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Data sourse: GSE105028, GSE126634, GSE152721, GSE165895
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Cell type: HFFc6, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 47%,
"4_Tx": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, NANOG, SMARCA2, FOXA2, MYCN, POU5F1, E2F7, SOX2, ZNF534, EZH2phosphoT487, ATF2, SMAD3, FOXA1, FOXF1, SRF, BAHD1, HOXB13, TBP, SMARCC1, HOXC5, YY1, SMC3, USP7, NEUROD1, MYC, NFIC, SMARCA4, RFX1, ZNF184, RAD21, BRG1, GRHL3, NRF1, ZNF532, PBX4, DAXX, OTX2, NKX2-1, GABPA, LHX2, TAL1, GATA3, STAT3, PBX3, SUPT5H, IKZF1, NFE2, CHD7, RUNX2, MED1, SOX11, GATA1, NR3C1, ZNF592, CEBPB, EOMES, TEAD1, NR2F2, NFE2L2, ESR1, C11orf30, ZNF334, PHOX2B, CTCF, TCF12, T, NIPBL, EP300, SP1, BHLHE40, AR, SPI1, GATA2, RBM25, FLI1, BRD4, ILF3, JUND, FOXP1, PRDM6, MRTFB, TEAD4, PDX1
- Target gene symbol (double-evidenced CRMs): TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops