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Basic information

CohesinDB ID: CDBP00418747

Locus: chr21-37145513-37146764

Data sourse: ENCSR000BLD, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE72082, ENCSR000BSB, GSE129526, ENCSR000BLY, GSE105028, ENCSR000ECE, ENCSR000EHX, ENCSR153HNT, GSE121355, GSE68388, GSE116344, GSE25021, GSE50893

Cell type: MCF-7, GM2630, H1-hESC, HCT-116, RH4, GM2610, Ishikawa, GM19238, SK-N-SH, K-562, HSPC, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 48%, "5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZSCAN5C, ZNF660, SOX2, MEIS2, XBP1, PATZ1, FOXA1, ZNF101, PBX2, LEO1, ZFHX2, ZNF596, ATF3, NFIC, ZFP64, ZNF362, CHD7, ZBTB44, RUNX3, IKZF3, ZNF189, MZF1, ZNF467, ZNF629, TEAD1, TRIM28, ZNF121, KLF6, KLF10, ESR1, CTCF, TCF12, JUN, EP300, ZNF695, GATA6, DPF2, SOX4, ZNF423, ZNF528, TEAD4, PDX1, RBPJ, EED, GLIS1, NANOG, CHD8, MYCN, POU5F1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, ZNF317, SRF, ERG2, HIC1, HOXC5, ZBTB21, ZNF329, ZNF341, NFKB2, MYC, ETS1, EOMES, TSHZ1, SMARCA4, RAD21, RXRA, NKX2-1, STAT3, NKX3-1, ZNF398, RCOR1, ZNF639, NR2F6, VDR, NR3C1, CEBPB, CREB1, EZH2, KLF8, FEZF1, EBF3, ZHX2, SPI1, HDAC2, SIX2, FLI1, SMARCA5, MRTFB, ZNF554, CEBPA, NKX2-2, HDAC1, ZFX, SMAD3, ZNF770, ERG3, ZNF18, ZNF549, PRDM10, MEF2A, SMARCC1, ZNF35, ZNF384, RUNX2, OSR2, ZNF184, PBX4, DAXX, ARNT, ATF2, ETV6, MAFB, ZNF10, SUPT5H, CDK8, FOS, MED1, ZNF680, SUPT16H, KLF9, SETDB1, RBM22, BCL11A, SP1, PHIP, FOXP1, SMC3, STAG1, ZNF394, CREM, EBF1, PAF1, ZNF600, ZSCAN16, ZNF692, ZNF30, WT1, ZNF574, MEF2C, CDK9, KDM1A, YY1, RELA, NEUROD1, JUNB, ISL1, ZIC2, HIF1A, OTX2, BATF, TAL1, MAX, HAND2, CEBPG, SP7, NR2F2, TP53, PKNOX1, ZSCAN22, NFKB1, EGR2, ELF3, T, ZNF843, AR, ZNF324, ZBTB42, HSF1, NOTCH3, BRD4, JUND, ILF3, MAZ, ZSCAN23, MEF2D, ZNF24

Target gene symbol (double-evidenced CRMs): TTC3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 24

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182670,

eachgene

Deatailed information for cohesin site CDBP00418747