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Basic information

CohesinDB ID: CDBP00418748

Locus: chr21-37149405-37149819

Data sourse: GSE206145-NatGen2015, GSE165895

Cell type: Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 43%, "4_Tx": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, CHD8, CEBPA, SOX2, ZNF692, ZSCAN16, SMAD3, ZNF317, GTF2B, FOXA1, DUX4, HOXB13, ERG, RELA, JUNB, ATF3, MYC, RUNX2, GATA4, SMARCA4, NFIC, ZBTB44, PBX4, ZNF532, ATF4, PRDM9, GABPA, STAT3, MAX, TAL1, SUPT5H, FOS, MITF, MED1, NR3C1, CEBPB, CEBPG, TEAD3, ZNF121, CEBPD, NFE2L2, ESR1, HNF1B, USF2, PHOX2B, JUN, CTCF, MAFK, NUTM1, BRD4, ZZZ3, FOSL2

Target gene symbol (double-evidenced CRMs): TTC3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182670,

eachgene

Deatailed information for cohesin site CDBP00418748