- Basic information
- CohesinDB ID: CDBP00418750
- Locus: chr21-37152332-37152680
-
Data sourse: GSE206145-NatGen2015, GSE67783
-
Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 63%,
"4_Tx": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CDX2, TRP47, OGG1, CEBPB, FOXA2, SMARCA4, SOX2, ZBTB48, DDX5, SPI1
- Target gene symbol (double-evidenced CRMs): VPS26C,TTC3,KCNJ6,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:33500000-33525000~~chr21:37150000-37175000,
chr21:37150000-37175000~~chr21:37250000-37275000,
chr21:37150000-37175000~~chr21:37275000-37300000,
chr21:37150000-37175000~~chr21:37350000-37375000,
chr21:37150000-37175000~~chr21:37375000-37400000,
chr21:37150000-37175000~~chr21:37450000-37475000,
chr21:37150000-37175000~~chr21:37500000-37525000,
chr21:37150000-37175000~~chr21:37575000-37600000,
chr21:37150000-37175000~~chr21:37625000-37650000,
chr21:37150000-37175000~~chr21:37650000-37675000,
chr21:37150000-37175000~~chr21:37900000-37925000,
chr21:37150000-37175000~~chr21:38150000-38175000,
chr21:37150000-37175000~~chr21:38325000-38350000,
chr21:37150000-37175000~~chr21:38350000-38375000,