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Basic information

CohesinDB ID: CDBP00418751

Locus: chr21-37152964-37155737

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE126634, GSE132649, GSE105028, GSE25021, GSE108869, ENCSR000EDW, GSE165895, ENCSR917QNE, GSE67783, GSE86191, GSE152721, GSE206145-NatGen2015, GSE116344, ENCSR000EEG, ENCSR338DUC, ENCSR000BLS, GSE206145, ENCSR167MTG, GSE110061, GSE111913, ENCSR054FKH, ENCSR153HNT, GSE83726

Cell type: RPE, H1-hESC, T-47D, Fibroblast, HCT-116, RH4, Hep-G2, HFFc6, HeLa-S3, RT-112, HSPC, K-562, Liver, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 8% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.833

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 41%, "4_Tx": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CDX2, TRP47, OGG1, CEBPB, FOXA2, SMARCA4, SOX2, ZBTB48, DDX5, SPI1

Target gene symbol (double-evidenced CRMs): TTC3,VPS26C,DYRK1A,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 234

Number of somatic mutations (non-coding): 61

Related genes and loops

Related gene: ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418751