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Basic information

CohesinDB ID: CDBP00418754

Locus: chr21-37164415-37164605

Data sourse: GSE25021, ENCSR153HNT

Cell type: K-562, MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 48%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, FOSL1, SMC1A, CEBPA, POU5F1, FOXA1, DDX5, CDK9, PBX2, SMARCC1, ERG, RELA, ASCL1, NEUROD1, ATF3, MYC, PRDM1, ARNT, ATF4, OTX2, ATF2, GLYR1, GABPA, MAX, MAFB, SUPT5H, CDK8, HAND2, CEBPG, ZNF592, CEBPB, CEBPD, MYB, ETV1, ESR1, C11orf30, MAFK, SPI1, NUTM1, ATF7, FLI1, BRD4, JUND, MLLT1, ZNF316

Target gene symbol (double-evidenced CRMs): DYRK1A,TTC3,KCNJ6,VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542,

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Deatailed information for cohesin site CDBP00418754