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Basic information

CohesinDB ID: CDBP00418758

Locus: chr21-37176615-37177604

Data sourse: ENCSR000BTQ, ENCSR000BTU, GSE67783, GSE72082, GSE86191, GSE129526, GSE111913, ENCSR153HNT, GSE68388, ENCSR703TNG, GSE25021

Cell type: MCF-7, HCT-116, Ishikawa, RT-112, K-562, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 57%, "5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, MEIS2, XBP1, FOXA1, PBX2, MLL4, TFAP4, HDGF, ZNF444, ZNF532, GLYR1, SMARCE1, MITF, TEAD1, KLF6, ZNF217, ESR1, HNF1B, LMO2, JUN, CTCF, BAF155, NUTM1, E4F1, MNT, DPF2, RFX5, RAD51, TEAD4, PDX1, TFAP2C, EED, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, TOP2A, CTBP1, ZNF317, ZBTB48, ZSCAN5A, ERG, MYC, RFX1, RAD21, GABPA, STAT3, NKX3-1, RCOR1, NFE2, DACH1, NR3C1, CEBPB, ESRRA, CREB1, GRHL2, ZHX2, SPI1, IRF1, HDAC2, GATAD2B, ZNF146, SIX2, NCOA2, RUNX1, CBX1, CEBPA, SIN3A, ZFX, SMAD3, ZNF770, ERG3, CREBBP, ZNF384, RUNX2, GATA4, PBX4, ARNT, PRDM9, PBX3, FOS, CDK8, SUPT5H, ZEB1, TEAD3, PIAS1, RBM22, USF1, BCL11A, HNF4A, RBM25, CTBP2, NCOR2, STAG1, CREM, PAF1, ZNF600, WT1, ZBTB33, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, TARDBP, HIF1A, GATA3, TAL1, MAX, NRIP1, GATA1, MTA1, ZNF143, KLF4, NCOA3, NR2F2, TP53, PKNOX1, ZNF687, ZNF334, ELF3, AR, PAX3-FOXO1, EGR1, NOTCH3, BRD4, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): TTC3,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182670, ENSG00000157542,

eachgene

Deatailed information for cohesin site CDBP00418758