- Basic information
- CohesinDB ID: CDBP00418767
- Locus: chr21-37197105-37197434
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 64%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, XBP1, FOXA1, LEO1, MLL4, ZFHX2, ATF3, ZFP64, PRDM1, ZNF532, ZNF736, CDX2, KLF5, ELF1, TEAD1, KLF6, ESR1, OCA2, HNF1B, CTCF, TCF12, JUN, EP300, NUTM1, SOX9, SOX4, E2F1, TEAD4, TFAP2C, GLIS1, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF263, POU5F1, RUNX1T1, CDK7, ZBTB48, ZSCAN5A, ERG2, HOXC5, ERG, OGG1, MYC, SMARCA4, EOMES, RAD21, LHX2, GRHL3, TOP1, PROX1, RXRA, APC, STAT3, SOX10, RCOR1, NR3C1, CEBPB, SRSF3, EZH2, SPI1, IRF1, MXD3, NCOA2, ETV5, RUNX1, CTNNB1, BCL6, CEBPA, ZFX, SMAD3, TET2, ERG3, NSD2, ZNF384, TAF15, RUNX2, CDK6, GATA4, OSR2, GR, ARNT, DAXX, PBX4, NRF1, PRDM9, FOXM1, FOS, SUPT5H, TEAD3, ZEB1, ZNF3, KLF9, ZNF41, RBM22, BCL11A, NIPBL, SP1, HNF4A, GSPT2, ZBTB7A, HNRNPLL, PHIP, FOXP1, AATF, SMC3, STAG1, TRP47, PPARG, FOXA2, CBX3, AGO1, TBL1X, PAF1, WT1, YY1, RELA, NEUROD1, JUNB, SP140, TCF4, HIF1A, OTX2, TAL1, MAX, ZNF143, AGO2, CBX2, KLF4, SP7, NCOA3, NEUROG2, NR2F1, TP53, MYOD1, ELF3, BRD2, BHLHE40, PAX3-FOXO1, AR, ZBTB16, RXR, EGR1, ZBTB26, NCOR1, HSF1, BRD4, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): KCNJ6,TTC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000182670,
ENSG00000157542,
- Related loop:
chr21:34350000-34375000~~chr21:37200000-37225000,
chr21:36975000-37000000~~chr21:37200000-37225000,
chr21:37175000-37200000~~chr21:37625000-37650000,
chr21:37200000-37225000~~chr21:37425000-37450000,
chr21:37200000-37225000~~chr21:37475000-37500000,
chr21:37200000-37225000~~chr21:37525000-37550000,
chr21:37200000-37225000~~chr21:37550000-37575000,
chr21:37200000-37225000~~chr21:37625000-37650000,
chr21:37200000-37225000~~chr21:37650000-37675000,