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Basic information

CohesinDB ID: CDBP00418774

Locus: chr21-37215161-37218095

Data sourse: GSE67783, GSE86191, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 90% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 73%, "5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF384, CEBPG, CEBPB, TEAD3, CEBPA, CEBPD, ZNF362, ZFX, XBP1, ZNF532, ZNF48, HLF, MAZ, SMAD4, ZNF22, HNF4G, AHR, HNF4A

Target gene symbol (double-evidenced CRMs): HLCS,KCNJ6,DYRK1A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene: ENSG00000159267, ENSG00000157540, ENSG00000157542,

eachgene

Deatailed information for cohesin site CDBP00418774