- Basic information
- CohesinDB ID: CDBP00418779
- Locus: chr21-37233610-37234227
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Data sourse: GSE86191, GSE67783, ENCSR153HNT, GSE83726
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Cell type: K-562, RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 67%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, SOX2, XBP1, FOXA1, LEO1, HDGF, ATF3, NFIC, RUNX3, CHD7, ZNF532, CBFB, PAX5, TEAD1, ZNF121, BCLAF1, RBM39, ELF1, SNAI2, ZNF217, ESR1, OCA2, USF2, CTCF, SND1, TCF12, NUTM1, MNT, DPF2, E2F6, IRF4, RFX5, GTF2F1, PDX1, RBPJ, EED, JARID2, POU2F2, BRD1, ZSCAN5D, MYCN, ZNF263, POU5F1, CTBP1, MTA2, ZBTB48, ZSCAN5A, STAT1, ARID3A, ASCL1, OGG1, MYC, ONECUT1, GRHL3, STAT3, PRDM14, IKZF1, DNMT3B, TERF2, NR3C1, CREB1, EZH2, GRHL2, SPI1, ZNF257, HDAC2, GATAD2B, MXD3, FLI1, SMARCA5, RELB, HCFC1R1, PTBP1, RUNX1, MAFG, SMC1A, CEBPA, FIP1L1, ZFX, ZNF770, TET2, TRIM22, ZNF18, MEF2A, RARA, CREBBP, ZBTB2, TAF15, ARNT, ATF2, ETV6, MAFB, FOXM1, SUPT5H, SMARCB1, CHD1, MED1, ZEB1, SCRT2, ZNF3, C11orf30, SETDB1, RBM22, MAFK, NIPBL, SP1, BCL11A, ARID2, ATF7, ASH2L, HNRNPLL, TCF3, AATF, SMC3, STAG1, MLLT1, NFATC3, TRP47, CBFA2T2, MEF2B, FOXA2, AGO1, TBL1X, CREM, PAF1, EBF1, MTA3, ZBED1, WT1, MAFF, GTF2B, MEF2C, CDK9, YY1, RELA, TARDBP, JUNB, AHR, NEUROD1, SP140, TCF4, SKIL, HIF1A, GATA3, BATF, MAX, GATA1, AGO2, ZNF143, KLF4, NR2F1, KDM5B, ZNF687, PKNOX1, ZNF334, TBX21, BHLHE40, AR, TAF1, ZBTB40, RXR, HEXIM1, HSF1, ZBTB26, IKZF2, BRD4, SCRT1, CLOCK, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): KCNJ6,HLCS,VPS26C,DYRK1A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000157538,
ENSG00000157540,
ENSG00000157542,
- Related loop:
chr21:36975000-37000000~~chr21:37225000-37250000,
chr21:37225000-37250000~~chr21:37425000-37450000,
chr21:37225000-37250000~~chr21:37475000-37500000,
chr21:37225000-37250000~~chr21:37525000-37550000,
chr21:37225000-37250000~~chr21:37550000-37575000,
chr21:37225000-37250000~~chr21:37575000-37600000,
chr21:37225000-37250000~~chr21:37600000-37625000,
chr21:37225000-37250000~~chr21:37625000-37650000,
chr21:37225000-37250000~~chr21:37650000-37675000,
chr21:37225000-37250000~~chr21:37900000-37925000,