Browse_each

Basic information

CohesinDB ID: CDBP00418790

Locus: chr21-37259350-37259929

Data sourse: GSE206145-NatGen2015, ENCSR153HNT

Cell type: K-562, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 59%, "7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, HLF, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, MEN1, ZBTB44, MORC2, PAX5, SNAPC1, TEAD1, LMO2, OCA2, ZNF561, ARID5B, E4F1, SOX5, E2F4, ZNF528, KMT2B, GATAD2A, NANOG, BRD3, ZNF263, POU5F1, CTBP1, ZMYND11, DUX4, STAT1, ZNF134, SAP130, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, FOXK2, UBN1, ZNF398, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, HCFC1, MXI1, ZNF785, RELB, RUNX1, CEBPA, NKX2-2, HDAC1, REPIN1, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, TFDP1, ZBTB10, ATF2, SATB1, SP2, SMARCB1, TERF1, PML, PIAS1, SMAD1, NR1H2, EVI1, IKZF5, ARID2, ETV4, NFATC3, CBFA2T2, MEF2B, ZNF207, CREM, CHD2, NFATC1, PAF1, ZSCAN16, WT1, MEF2C, NEUROD1, ZFP36, TCF4, BATF, PLAG1, KLF4, BCL11B, ZFP69B, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, FOSL1, ZNF660, XBP1, HNRNPK, THRB, ATF3, ZFP64, RUNX3, ZNF532, CBFB, TP63, ZSCAN4, MITF, ZNF467, JMJD1C, INTS11, MAF, ELF1, RBM39, SNAI2, SMAD5, CTCF, JUN, L3MBTL4, ZBTB20, MNT, LMO1, RYBP, DPF2, IRF4, ZNF423, PDX1, MLX, TFAP2C, RBPJ, ZNF239, ZSCAN21, ZBTB17, ZBTB48, NONO, SRF, DDX5, NBN, ZNF2, HOMEZ, FOXP2, KDM4A, TSHZ1, RXRA, PRDM14, MIER3, HNRNPH1, TERF2, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, NFIL3, THAP11, SOX13, AFF4, POU4F2, ZNF770, ZNF18, SP3, ARNT, BACH1, DAXX, ZNF48, ZEB2, PBX3, ETV6, ZNF10, NCAPH2, HMGXB4, TEAD3, ZXDB, U2AF1, TAF7, KLF9, USF1, SP1, BCL11A, ATF7, ASH2L, GLIS2, PRDM6, SMC3, MLLT1, STAG1, ZNF394, TRP47, AGO1, EBF1, ZNF580, BCL3, KDM1A, BRG1, ZIC2, PCGF1, GATA3, TAL1, NRIP1, ZNF143, AGO2, MTA1, TP53, ZNF334, NFKB1, ZSCAN22, PHF5A, BRD2, KAT8, ARRB1, TBX21, EGR1, RB1, RNF2, IKZF2, BRD4, JUND, ZSCAN23, PGR, FANCL, SOX2, PATZ1, LEO1, RING1B, TFAP4, SIN3B, CHD7, ZNF444, MXD4, ZNF189, MZF1, KLF6, ZNF217, SAP30, ESR1, TP73, ZNF524, SND1, KLF1, SOX9, SOX4, E2F6, TRIM24, GTF2F1, GLIS1, POU2F2, KDM4C, ZSCAN5A, ZMYND8, ERG2, SP4, HIC1, TBP, HOXC5, OGG1, ETS1, MYC, ARID1B, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, SRSF3, EZH2, ZNF652, PHF8, SPI1, PCBP1, HDAC2, INTS13, GATAD2B, ZNF76, NCOA2, ETV5, BCL6, SIN3A, ERG3, RARA, NFYC, CREBBP, ZNF384, TAF15, SMAD4, ZNF518A, CDK8, ZEB1, SUPT16H, NCOA1, SREBF2, RBM22, HNF4A, NR4A1, REST, ARID1A, HNRNPLL, BCOR, FOXP1, AATF, NCOR2, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, FOXO3, RELA, TARDBP, SKIL, MAX, ZNF592, GFI1B, NR2F1, NEUROG2, KDM5B, PKNOX1, T, AR, ZNF324, HEXIM1, AHR, DMAP1, MBD3, FOSL2, ZNF391, HMG20A, HMGN3, SUZ12, RBFOX2, ZFHX2, LYL1, CTCFL, PRDM1, KLF14, MECOM, CDX2, ZNF629, KLF5, BCLAF1, TRIM28, RCOR2, HNF1B, USF2, TCF12, EP300, NUTM1, BAF155, PRDM4, GLI4, E2F1, SMC1, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, RUNX1T1, CDK7, MLLT3, GATAD1, ARID3A, ZNF341, RAD21, GRHL3, ZNF614, XRCC5, NFE2, ZNF639, FEZF1, TFE3, EHF, HBP1, IRF1, ZNF664, SREBF1, ZGPAT, MRTFB, PTBP1, SMC1A, CBX1, ZNF335, FIP1L1, ZFX, SMAD3, PCBP2, TWIST1, IRF2, NOTCH1, RUNX2, CDK6, GATA4, OSR2, NRF1, PBX4, SUPT5H, CHD1, FOS, TGIF2, MED1, CEBPD, MYB, KDM6B, SCRT2, ZNF3, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, FOXA2, RBBP5, E2F8, ZNF600, MIER2, FOXF1, ZBTB33, HOXB13, YY1, ZNF610, SP140, BRCA1, HIF1A, OTX2, ZNF449, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF687, BHLHE40, NFKBIZ, TAF1, ZNF579, ZBTB40, ZBTB42, NOTCH3, CLOCK, MAZ, ZNF24

Target gene symbol (double-evidenced CRMs): VPS26C,KCNJ15,DYRK1A,HLCS,TTC3,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542, ENSG00000157551,

eachgene

Deatailed information for cohesin site CDBP00418790