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Basic information

CohesinDB ID: CDBP00418793

Locus: chr21-37270551-37271438

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, GSE116868, ENCSR153HNT

Cell type: K-562, H1-hESC, MCF-7, MB157

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 64%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SOX2, FOXA1, RBFOX2, PBX2, HDGF, BMI1, ZNF444, SMARCE1, TP63, ELF1, TRIM28, TEAD1, ZNF217, ESR1, CTCF, TCF12, BAF155, EP300, DPF2, E2F1, GTF2F1, TFAP2C, EED, ZNF263, MYCN, CTBP1, ZNF317, ERF, ZBTB48, ZSCAN5A, TBP, ERG, SMARCA4, NKX2-1, STAT3, XRCC5, IKZF1, RCOR1, ZNF750, ESRRA, NR3C1, CEBPB, CREB1, GRHL2, TRPS1, HDAC2, GATA2, ZNF644, GATAD2B, RUNX1, CBX1, SIN3A, ZFX, SMAD3, CREBBP, ZXDC, ARNT, NFIB, PBX4, SUPT5H, CHD1, PIAS1, L3MBTL2, TFAP2A, ASH2L, CTBP2, FOXP1, CBX3, PAF1, WT1, ZBTB33, HOXB13, ZKSCAN1, KDM1A, YY1, TARDBP, NEUROD1, SP140, HIF1A, GATA3, MAX, GATA1, KLF4, ZNF592, NCOA3, NR2F2, KDM5B, ZNF687, PKNOX1, ZNF334, AR, ZBTB40, EGLN2, EGR1, BRD4, CLOCK, CUX1, MAZ, ZNF24, ZFP42, AHR

Target gene symbol (double-evidenced CRMs): TTC3,HLCS,DYRK1A,KCNJ6,KCNJ15,VPS26C

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157538, ENSG00000157540, ENSG00000157542, ENSG00000157551,

eachgene

Deatailed information for cohesin site CDBP00418793