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Basic information

CohesinDB ID: CDBP00418795

Locus: chr21-37272945-37273597

Data sourse: GSE105028, GSE62063, ENCSR153HNT

Cell type: K-562, Ramos, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SOX2, XBP1, PATZ1, FOXA1, ZFHX2, HNRNPK, TFAP4, ZFP64, CHD7, PRDM1, RUNX3, MECOM, MZF1, ZNF467, BCLAF1, TRIM28, CTCF, TCF12, DPF2, IRF4, RBPJ, EED, GLIS1, NANOG, POU2F2, ZNF263, BRD3, MTA2, ZBTB17, ZBTB48, ERG2, SP4, ERG, NFKB2, MYC, KDM4A, RAD21, STAT3, ZNF398, IKZF1, EZH2, KLF8, SPI1, PCBP1, RELB, ETV5, RUNX1, ZNF335, PCBP2, ERG3, ZNF513, SMARCC1, PRDM10, SP3, SP2, MED1, STAT5A, MAFK, SP1, BCL11A, ATF7, ASH2L, PHIP, TCF3, ZNF207, GTF2B, MAFF, CDK9, KDM1A, YY1, RELA, TARDBP, ZNF148, JUNB, SKIL, HIF1A, BATF, MAX, ZNF143, KDM5B, ZBTB6, PKNOX1, NFKB1, EGR2, BRD2, T, ZNF366, HSF1, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): TTC3,HLCS,KCNJ6,DYRK1A,KCNJ15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157540, ENSG00000157542, ENSG00000157551,

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Deatailed information for cohesin site CDBP00418795