- Basic information
- CohesinDB ID: CDBP00418796
- Locus: chr21-37274026-37274267
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Data sourse: GSE105028, GSE50893
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Cell type: GM12878, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, XBP1, PATZ1, FOXA1, ZFHX2, HNRNPK, TFAP4, ZFP64, CHD7, PRDM1, RUNX3, MECOM, MZF1, ZNF467, BCLAF1, TRIM28, CTCF, TCF12, DPF2, IRF4, RBPJ, EED, GLIS1, NANOG, POU2F2, ZNF263, BRD3, MTA2, ZBTB17, ZBTB48, ERG2, SP4, ERG, NFKB2, MYC, KDM4A, RAD21, STAT3, ZNF398, IKZF1, EZH2, KLF8, SPI1, PCBP1, RELB, ETV5, RUNX1, ZNF335, PCBP2, ERG3, ZNF513, SMARCC1, PRDM10, SP3, SP2, MED1, STAT5A, MAFK, SP1, BCL11A, ATF7, ASH2L, PHIP, TCF3, ZNF207, GTF2B, MAFF, CDK9, KDM1A, YY1, RELA, TARDBP, ZNF148, JUNB, SKIL, HIF1A, BATF, MAX, ZNF143, KDM5B, ZBTB6, PKNOX1, NFKB1, EGR2, BRD2, T, ZNF366, HSF1, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): KCNJ15,DYRK1A,TTC3,KCNJ6,HLCS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159267,
ENSG00000182670,
ENSG00000157540,
ENSG00000157542,
ENSG00000157551,
- Related loop:
chr21:34350000-34375000~~chr21:37250000-37275000,
chr21:34350000-34375000~~chr21:37275000-37300000,
chr21:34600000-34625000~~chr21:37250000-37275000,
chr21:36950000-36975000~~chr21:37250000-37275000,
chr21:36975000-37000000~~chr21:37250000-37275000,
chr21:37050000-37075000~~chr21:37250000-37275000,
chr21:37150000-37175000~~chr21:37250000-37275000,
chr21:37150000-37175000~~chr21:37275000-37300000,
chr21:37250000-37275000~~chr21:37350000-37375000,
chr21:37250000-37275000~~chr21:37375000-37400000,
chr21:37250000-37275000~~chr21:37425000-37450000,
chr21:37250000-37275000~~chr21:37450000-37475000,
chr21:37250000-37275000~~chr21:37550000-37575000,
chr21:37250000-37275000~~chr21:37575000-37600000,
chr21:37250000-37275000~~chr21:37625000-37650000,
chr21:37250000-37275000~~chr21:37650000-37675000,
chr21:37250000-37275000~~chr21:37850000-37875000,
chr21:37250000-37275000~~chr21:38225000-38250000,
chr21:37250000-37275000~~chr21:38250000-38275000,