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Basic information

CohesinDB ID: CDBP00418797

Locus: chr21-37274761-37275372

Data sourse: GSE206145, GSE206145-NatGen2015, GSE62063, GSE111913

Cell type: RPE, Fibroblast, RT-112, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,SA1,Rad21,SMC1,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 94% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 74%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF394, ZNF426, ZNF697, ZNF433, ZNF101, ZNF654, ZNF18, ZBTB21, ZBTB8A, ZNF266, ZFP64, ZNF510, PRDM12, ZNF781, ZNF518A, ZNF189, ZNF639, ZNF629, ZXDB, ZNF558, ZBTB11, ZNF680, ZNF791, ZNF213, FEZF1, ZNF292, ZNF140, ZNF577, CTCF, ZNF664, REST, ZNF623, ZC3H11A, ZNF555, ZNF34

Target gene symbol (double-evidenced CRMs): TTC3,KCNJ6,DYRK1A,KCNJ15,HLCS

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000159267, ENSG00000182670, ENSG00000157540, ENSG00000157542, ENSG00000157551,

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Deatailed information for cohesin site CDBP00418797