Deatailed information for cohesin site CDBP00418810


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  • Basic information
  • CohesinDB ID: CDBP00418810
  • Locus: chr21-37299004-37300165
  • Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT
  • Cell type: K-562, Fibroblast, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 94% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 78%, "14_ReprPCWk": 16%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, PGR, POU2F2, SMC1A, ZSCAN5D, ZNF263, MYCN, CHD8, ZFX, CTBP1, XBP1, ZBTB48, ZSCAN5A, WT1, ZNF770, PBX2, ETV5, YY1, RELA, ATF3, RUNX2, ZFP64, THAP1, SP140, ZFP36, GRHL3, ZNF429, HIF1A, PRDM9, ZNF143, IKZF1, TERF2, PLAG1, NR3C1, MYOG, ZNF573, TP53, ESR1, OCA2, MYOD1, CTCF, BCL11A, ARRB1, EGLN2, SIX2, NOTCH3, SCRT1, BRD4, SMC3, STAG1, RBPJ
  • Target gene symbol (double-evidenced CRMs): TTC3
  • Function elements
  • Human SNPs: 3-hydroxy-1-methylpropylmercapturic_acid_levels_in_smokers
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 3
  • Related genes and loops

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