- Basic information
- CohesinDB ID: CDBP00418823
- Locus: chr21-37336732-37337118
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 92%,
"14_ReprPCWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOXA1, HLF, RXRB, MLL4, KDM3A, HDGF, ZBTB44, IKZF3, TEAD1, ZNF121, PITX3, HDAC8, ZNF561, E4F1, SOX5, PYGO2, ZNF528, GATAD2A, ZNF263, POU5F1, TOP2A, BRD3, CTBP1, ZMYND11, STAT1, ZNF134, SAP130, ERG, ZBTB21, ZBTB8A, SMARCA4, RFX1, FOXK2, UBN1, ZNF398, RCOR1, DACH1, NFRKB, NR2F6, CEBPB, CREB1, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, FLI1, DRAP1, NR2C2, MXI1, HCFC1, EP400, RUNX1, HDAC1, CEBPA, NKX2-2, TBX3, SMARCC1, PRDM10, ZBTB2, TFDP1, ZBTB10, ATF2, FOXM1, SP2, GMEB1, C11orf30, MBD1, STAT5A, IKZF5, RBM25, AFF1, ELL2, CBFA2T2, CBX3, CREM, CHD2, ZSCAN16, WT1, MEF2C, CREB3L1, NEUROD1, JUNB, TCF4, KLF4, ZFP69B, ZBTB6, EGR2, ELF3, ARID4B, RXR, ZNF366, MAML3, HSF1, NCOR1, ZBTB26, ILF3, ZNF316, FOSL1, SMARCA2, ZNF660, XBP1, PBX2, THRB, ATF3, ZFP64, TP63, ZSCAN4, ZNF467, ELF1, SNAI2, KLF10, CTCF, JUN, MNT, ZBTB20, DPF2, ZNF280A, PDX1, RBPJ, MLX, TFAP2C, ZNF317, MTA2, ZBTB48, ZBTB17, ZSCAN21, SRF, NBN, ONECUT1, ZNF2, HOMEZ, TSHZ1, RXRA, NKX3-1, MIER3, TEAD2, LEF1, VDR, NR3C1, ESRRA, FOXK1, TBL1XR1, KLF8, GRHL2, EBF3, NFIL3, THAP11, ZBTB24, EZH2phosphoT487, SOX13, AFF4, POU4F2, ZNF18, SP3, DAXX, ARNT, BACH1, NFIB, PRDM9, ZEB2, HMBOX1, PBX3, MAFB, ZNF10, ETV6, HMGXB4, TEAD3, ZXDB, TBX5, USF1, BCL11A, SP1, TFAP2A, ATF7, ASH2L, GLIS2, PRDM6, ZNF623, SMC3, MLLT1, STAG2, STAG1, ZNF394, MTA3, MAFF, ESR2, ZNF580, BCL3, KDM1A, ISL1, ZIC2, GATA3, TAL1, NRIP1, ZNF143, MTA1, TP53, ZSCAN22, NFKB1, PHOX2B, BRD2, PHF5A, KAT8, EGR1, RNF2, BRD4, JUND, CUX1, ZSCAN23, TBX2, PGR, SOX2, PATZ1, UBTF, TFAP4, CHD7, ATF4, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, KLF1, ZNF695, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, ZSCAN5A, ZMYND8, BAHD1, ERG2, SP4, TBP, HOXC5, SMARCC2, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, ZNF343, DNMT3B, EZH2, ZNF652, MRTFA, NFE2L1, SPI1, HDAC2, INTS13, GATAD2B, TAF9B, NFYB, ZNF554, NCOA2, ETV5, BCL6, SIN3A, ZFP37, ERG3, MEF2A, RARA, ZNF384, CREBBP, ZNF35, HMGB2, ZNF518A, SMAD4, CBFA2T3, CDK8, ZEB1, SPDEF, ZMYM3, NCOA1, MAFK, NR4A1, HNF4A, REST, ZHX1, HNRNPLL, BCOR, FOXP1, PTTG1, PPARG, ZNF692, GTF2B, ZNF30, ZNF574, TCF7, ZNF318, RELA, TARDBP, SKIL, MGA, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, NEUROG2, PKNOX1, MYOD1, AR, PAX3-FOXO1, YAP1, ZNF324, RBAK, ZNF280D, DMAP1, FOSL2, AHR, ZNF391, HMG20A, MEIS2, SUZ12, RBFOX2, ZFHX2, INSM2, NFIC, ZNF362, PRDM1, CDX2, ZNF629, KLF5, TRIM28, ETV1, RCOR2, USF2, TCF12, EP300, BAF155, GATA6, PRDM4, CREB3, SOX6, RAD51, E2F1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, CDK7, ID3, GATAD1, ARID3A, USP7, ASCL1, ZNF341, RAD21, PROX1, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ZNF750, FEZF1, TFE3, ZNF664, IRF1, ZGPAT, MRTFB, ATF1, MAFG, SMC1A, ZNF335, ZFX, SMAD3, TWIST1, BRD9, RUNX2, CDK6, GATA4, OSR2, GR, ZNF184, ZSCAN30, NRF1, PBX4, NR2C1, FOS, TGIF2, MED1, ZNF558, L3MBTL2, SETDB1, KLF16, NUP98-HOXA9, NIPBL, ZBTB7A, PHIP, TCF3, SKI, KLF13, FOXA2, RBBP5, ZNF600, HOXB13, ZNF589, YY1, ZNF148, BRCA1, SP140, ZNF610, HIF1A, GATA1, HAND2, SP7, NCOA3, NR2F2, ZNF83, ZNF512, ZNF687, ZNF843, NFKBIZ, BHLHE40, PTRF, TAF1, ZBTB40, ZBTB42, MYNN, NOTCH3, ZNF248, MAZ, ZNF440, MEF2D, ZNF24
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops