- Basic information
- CohesinDB ID: CDBP00418825
- Locus: chr21-37340676-37343392
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Data sourse: ENCSR000BLD, GSE105004, GSE67783, GSE138405, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR000EDE, ENCSR000EHX, ENCSR153HNT, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: RPE, H1-hESC, Fibroblast, Hela-Kyoto, Monocytes, HeLa-S3, HeLa, SK-N-SH, K-562, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
94% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMARCA2, ZSCAN5C, MEIS2, PBX2, ZFHX2, NFIC, ZNF362, TP63, ZNF467, ELF1, TRIM28, ETV1, ESR1, OCA2, PITX3, JUN, TCF12, EP300, ZBTB20, GATA6, DPF2, PRDM4, TRIM24, E2F4, TEAD4, GLIS1, BRD3, ZNF263, MYCN, ZBTB17, DUX4, ZSCAN5A, SRF, ERG2, HOXC5, ERG, ZBTB8A, ETS1, MYC, ARID1B, RAD21, GRHL3, RXRA, STAT3, UBN1, ZNF398, RCOR1, VDR, ZNF750, CEBPB, ESRRA, KLF8, GRHL2, EBF3, SPI1, ZNF786, EHF, GATA2, FLI1, MRTFB, ZFX, SMAD3, ZNF770, ERG3, SMARCC1, PRDM10, RARA, ZNF35, RUNX2, GATA4, OSR2, PBX4, NRF1, DAXX, ZNF518A, PBX3, FOS, CDK8, ZEB1, SETDB1, USF1, REST, PHIP, PRDM6, ELL2, ZNF394, CHD2, ZNF600, ZSCAN16, WT1, ZBTB33, KDM1A, YY1, RELA, ISL1, GATA3, TAL1, MAX, HAND2, KLF4, SP7, NCOA3, KDM5B, PKNOX1, ZSCAN22, EGR2, PHOX2B, BRD2, AR, TAF1, EGLN2, ZNF366, EGR1, MAML3, NOTCH3, BRD4, JUND, MAZ, TBX2, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 18
- Related genes and loops